BONE METASTASES

This study looks at whether giving radiation early to high-risk bone spots (that are not causing pain yet) can prevent future fractures or other bone complications in people with advanced solid tumors. About 120 participants will be split into two groups: one gets standard care (…

This study follows 50 people with cancer that has spread to the bones (but only a few spots) to see if freezing those spots with cryoablation can stop them from growing. The goal is to control the disease, reduce pain, and improve quality of life. Participants will have the proce…

This study is testing a highly precise radiation technique called SBRT for people with cancer that has spread to the spine. The goal is to see how safe and effective this treatment is when used in regular hospital practice. About 100 adults will take part, and researchers will tr…

This study tests whether a single, quick radiation treatment for painful bone metastases can be done in just one hospital visit, skipping the usual planning session. About 40 adults with cancer and up to two painful bone spots will receive this streamlined therapy. The goal is to…

This study tests whether a newer, more precise type of radiation (SBRT) works better than standard radiation for reducing pain from cancer that has spread to the bones. About 220 adults with solid tumors or multiple myeloma who have bone pain will be randomly assigned to one of t…

This study is testing whether a procedure called arterial embolization can reduce pain and improve quality of life in people with bone metastases (cancer that has spread to the bones). The procedure blocks blood flow to the tumor, which may shrink it and ease symptoms. Researcher…

This study tests whether adding a non-opioid painkiller (ketorolac) to standard opioid pain medicine can reduce the amount of opioids needed after preventive thigh bone surgery. The surgery is for patients with cancer that has spread to the thigh bone but who do not have a broken…

This study is collecting information from 2500 people with cancer that has spread to the bones (bone metastases) who are receiving radiation therapy. The goal is to learn why only about 60% of patients get pain relief and to build tools that help doctors predict who will benefit …

This study looks back at 600 patients who had surgery for a broken or about-to-break upper thigh bone caused by cancer that spread from elsewhere. The goal is to compare two types of surgery—a metal rod inside the bone or a replacement joint—to see which one lasts longer, has few…

This study gathers medical records, scans, and lab results from 250 adults with bone metastases (cancer that spread to bones). The goal is to create a dataset called RAW, which researchers will use to develop computer models that better predict fracture risk and life expectancy. …

This study is building a database of health information from 500 adults with painful bone metastases that have spread from other cancers. Researchers will track participants over time to learn more about the disease and how different treatments affect survival. The goal is to gat…