BIPOLAR II DISORDER

This study looked at whether repeated ketamine infusions can help people with bipolar depression who did not get better with other treatments. 41 adults who already responded to an initial course of ketamine received up to 6 more infusions over 12 weeks. The goal was to see if th…

This study tested whether repeated doses of intravenous ketamine can safely and effectively reduce depression in people with bipolar disorder who haven't responded to other treatments. 71 adults with bipolar I or II and current major depression received four ketamine infusions or…

This study tested an experimental drug called ABBV-932 in 161 adults with bipolar I or II disorder who were currently experiencing a depressive episode. Participants took either the drug or a placebo daily for 6 weeks to see if it safely improves mood and reduces depression sympt…

This study tested an investigational medication called BXCL501 for calming agitation episodes in people with bipolar disorder, schizophrenia, or related conditions. 452 participants received either the drug or a placebo, and researchers measured changes in agitation levels and sa…

This study looked at whether family members or caregivers can help measure agitation in people with bipolar disorder or schizophrenia. 33 adults took a single dose of an experimental medicine, and researchers compared ratings from doctors, patients, and their family members. The …