Ketamine shows promise for bipolar depression in new trial
NCT ID NCT05004896
First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 24 times
Summary
This study tested whether repeated doses of intravenous ketamine can safely and effectively reduce depression in people with bipolar disorder who haven't responded to other treatments. 71 adults with bipolar I or II and current major depression received four ketamine infusions or a placebo (midazolam) over two weeks. The goal was to measure changes in depression severity, suicidal thoughts, and quality of life.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Ontario Shores Centre for Mental Health Sciences
Whitby, Ontario, L1N 5S9, Canada
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Toronto General Hospital
Toronto, Ontario, M5G 2C4, Canada
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Toronto Western Hospital
Toronto, Ontario, M5T 2S8, Canada
Conditions
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