BILIARY TRACT CANCER

This study tracked side effects in 236 people with advanced bile duct cancer that cannot be removed by surgery. Participants received the drug IMFINZI together with two standard chemotherapy drugs. The goal was to see how often unwanted reactions occur in real-world use, not to t…

This study tested two different drug combinations in 93 people with advanced bile duct cancer that could not be removed by surgery. The goal was to see how long the cancer could be kept from growing. This is not a cure, but aims to control the disease and improve survival.

This study tested a combination of three drugs (mFOLFOX6, bevacizumab, and atezolizumab) in 20 people with advanced bile duct cancer who had already tried one prior treatment. The goal was to see if this combination could shrink tumors or slow the disease. The drugs were given ev…

This study tested a combination of the immunotherapy drug nivolumab with three chemotherapy drugs (nanoliposomal-irinotecan, 5-fluorouracil, and leucovorin) in 34 people with advanced biliary tract cancer that had worsened after initial treatment. The goal was to see if the combo…

This study tested the drug nivolumab in 54 people with advanced bile duct or gallbladder cancers that had stopped responding to standard treatments. Nivolumab is an immunotherapy that helps the immune system attack cancer cells. The main goal was to see if tumors shrank after fou…

This study tested a combination of three drugs (capecitabine, lenvatinib, and tislelizumab) given after surgery to 65 adults with biliary tract cancer. The goal was to see if this treatment could help keep cancer from coming back and improve survival. The study is complete, and r…

This study looks at how well the drug T-DXd works compared to usual treatments for people with advanced HER2-positive solid tumors (like lung, colon, and ovarian cancers). Researchers will use data from past clinical trials and real-world patient records to compare survival rates…

This study looked at whether two simple frailty tests (G8 and VES-13) can predict serious side effects from chemotherapy in people 65 and older with gastrointestinal cancers. Researchers followed 72 patients during their treatment to see if those who were frail had more toxicity.…

This study created a registry to collect information from 159 people with biliary tract cancers, including gallbladder cancer. The goal was to track treatments, quality of life, and health history to help researchers better understand these cancers and improve future care. Partic…

This study looked at 159 people with advanced colorectal, pancreatic, biliary, or esophageal cancers to see if simple blood tests (tumor markers and liquid biopsies) and patient-reported symptoms could predict whether the cancer would get worse. Researchers compared changes in th…

This study reviewed medical records of 729 people in Japan with biliary tract cancer that could not be removed by surgery. Researchers wanted to see if bile duct problems (like blockages or infections) that required hospital care affected how long patients could stay on their fir…