BILIARY ATRESIA

This study looks at whether a special diet high in medium-chain triglycerides (a type of fat that is easier to digest) can help infants with biliary atresia grow better after their Kasai surgery. About 300 babies under 3 months old will take part. Researchers will track their wei…

This study tests whether giving oral antibiotics preventively can lower the chance of cholangitis (a serious bile duct infection) in infants with biliary atresia after Kasai portoenterostomy surgery. About 356 babies will be randomly assigned to receive antibiotics or not, and fo…

This study tests whether a special high-MCT nutritional formula given before and after Kasai surgery can improve growth in infants with biliary atresia, a rare liver disease. About 120 infants under 3 months old will receive either the special formula or standard feeding. The goa…

This study is testing a new way to diagnose biliary atresia, a serious liver condition in newborns where bile ducts are blocked. Infants with jaundice will receive a one-time injection of a safe dye (ICG), and their diapers will be checked for a glow that indicates bile flow. The…

This study tests whether a safe fluorescent dye called indocyanine green (ICG) can help diagnose biliary atresia, a rare liver disease in infants. After injection, the dye normally appears in stool if bile ducts are open. In babies with biliary atresia, the dye should be absent. …

This study aims to learn more about biliary atresia, a rare liver disease in children. Researchers will collect medical information, genetic material, and body fluid samples from 1,265 participants aged 6 months to 20 years who still have their native liver. The goal is to find g…

This study aims to uncover the genetic causes of biliary atresia, a rare liver disease in newborns that often leads to liver failure and transplant. Researchers will analyze DNA from 1,100 children who have or will receive a liver transplant. The goal is to identify gene pathways…

This study looks at whether a substance called FGF19 in the blood before surgery can help predict how well babies with biliary atresia will recover. Researchers will follow 200 infants for one year after surgery to see if FGF19 levels relate to liver health and survival without a…

This study is building a large database of medical information and biological samples from infants with cholestasis (a liver condition that causes jaundice). Researchers will track how the disease changes over time in up to 1,000 babies. The goal is to learn more about these rare…