BEHAVIORAL SYMPTOMS

This study tests a remote, non-drug program called Regulating Together for children ages 8–17 with Tuberous Sclerosis Complex (TSC) who have emotional or behavioral challenges. About 105 kids and their caregivers will participate from home using video calls. The goal is to see if…

This study tests whether a new drug called (2R,6R)-HNK can quickly improve symptoms in adults with major depression that hasn't responded to other treatments. About 50 participants will receive four infusions of the drug and four of a placebo over several weeks, with their mood a…

This study looks at bacteria in urine, the genital area, and stool of children with overactive bladder and daytime wetting, comparing them to healthy children. Researchers want to see if these bacteria differ between the groups and if they change with treatment or age. About 110 …

This study is testing a combination of two treatments for Black teenagers (ages 12-17) who are at risk for suicide. The treatments are a type of therapy called Cognitive Behavioral Therapy for Suicide Prevention (CBT-SP) and a program where the teen chooses up to 5 caring adults …

This study follows 500 adults with depression, bipolar disorder, or suicide risk who are already receiving care. Researchers will use interviews, questionnaires, and optional tests like blood draws and brain scans to track how symptoms change over time. The goal is to find better…

This study looks at brain activity in children with overactive bladder and daytime wetting compared to healthy children. Researchers will use brain scans to see if a nerve stimulation treatment changes how the brain controls the bladder. About 65 children will take part, and the …

This study explores whether placing community health workers in rural schools can help students with poor attendance by addressing underlying social needs like housing, food, or healthcare. Researchers will work with about 38 students and their families to see if this approach is…