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Tiny bugs may explain why some kids wet their pants

NCT ID NCT07535619

Knowledge-focused Sponsor: Aalborg University Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at the bacteria found in urine, the genital area, and stool of children with overactive bladder and daytime wetting, comparing them to healthy children. Researchers want to see if these bacteria differ between the groups and if they change with treatment or as kids grow. The goal is to better understand the role of bacteria in bladder problems, not to test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 110 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2022

Expected to finish

Jun 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of 70 children with overactive bladder and daytime urinary incontinence and 40 healthy children without bladder symptoms. Children with OAB and DUI will be recruited from the involved pediatric departments, whereas healthy children without bladder symptoms will be recruited from the community.

Ages

5 to 17 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Overactive bladder as per International Children's Continence Society criteria (cases only). * At least two wet days per week (cases only). * No prior pharmacological treatment of OAB and DUI (cases only). * No lower urinary tract symptoms (healthy participants only). * Negative urine dipstick test Exclusion Criteria: * No known urogenital abnormality affecting the lower urinary tract function. * No known gastrointestinal or neurological diseases. * No use of systemic drugs within five half-lives of the drug. * No use of systemic antibiotics within three months before inclusion * No current urinary tract infection. * No urinary tract infection within the last three months prior to inclusion. * No current constipation. * Abnormal uroflowmetry (healthy participants only).

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Conditions

The condition(s) this trial relates to.

Behavioral Symptoms Diurnal Enuresis Elimination Disorders Lower Urinary Tract Symptoms overactive bladder Urinary Incontinence urinary system disorder Urination Disorders Urological Manifestations

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Behavioral symptoms Daytime wetting Elimination disorders Lower urinary tract symptoms Urinary incontinence Urination disorders Urologic diseases Urological manifestations

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    4 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Department of Pediatrics, Aalborg University Hospital

    RECRUITING

    Aalborg, 9000, Denmark

  • Department of Pediatrics, Aarhus University Hospital

    NOT_YET_RECRUITING

    Aarhus, 8200, Denmark

  • Department of Pediatrics, North Denmark Regional Hospital

    NOT_YET_RECRUITING

    Hjørring, 9800, Denmark

  • Department of Pediatrics, Regional Hospital West Jutland

    RECRUITING

    Herning, 7400, Denmark

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