BACTERIAL INFECTIONS

This study tested a new, simple blood culture system called BactInsight to diagnose bacterial infections faster in West Africa. Over 1,700 participants provided blood samples, which were tested with the new system and compared to standard methods. The goal was to see if the new s…

This study used artificial intelligence to find a set of proteins in the blood that can tell whether a fever is caused by bacteria or a virus. Researchers tested blood samples from 394 people with high fever and short illness. The goal is to create a quick test that helps doctors…

This early-phase study tested a new PET/CT imaging technique using a radioactive tracer called 11C-trimethoprim to see how it spreads in the body and how well it can find bacterial infections. About 16 adults with known or suspected infections took part. The goal was to measure t…

This study tested a radioactive tracer called 11C-PABA to see if it can help doctors find infections deep inside the body using PET scans. 13 healthy people and patients with infections, inflammation, or cancer took part. The goal was to see if this imaging method can tell infect…

This study tested whether giving mothers a single 2-gram dose of the antibiotic azithromycin during labour (or just before a C-section) could reduce the number of skin and soft tissue infections in their babies by 3 months of age. Over 2,100 pregnant women took part. The goal was…

This study tested if a special probiotic (Bifidobacterium breve PRL2020) could help children aged 3-12 who were taking common antibiotics for bacterial infections. The goal was to see if it could reduce diarrhea and other stomach issues like nausea and bloating. Researchers track…

This study looked at how a single dose of the antibiotic omadacycline works in the bodies of 23 children (ages 8 to 17) with bacterial infections. Researchers measured drug levels in the blood and checked for side effects. The goal was to gather safety and dosing information, not…

This early-stage study tested the safety and drug interaction of two antibiotics (cefiderocol and xeruborbactam) given together in 60 healthy adults. Participants were randomly assigned to receive the drug combination or a placebo. The goal was to see how the body processes the d…

This early-stage study tested a new oral drug combination (xeruborbactam prodrug plus ceftibuten) in 53 healthy adults aged 18 to 55. The main goal was to check safety, side effects, and how the drugs move through the body. No treatment was given for any illness; the study simply…

This study looks at why some medicines, like the antifungal drug voriconazole, can cause an extreme sunburn-like reaction called phototoxicity. Researchers will measure gene activity in the skin and blood of 62 people, including those taking voriconazole and healthy volunteers. T…