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Probiotic shows promise in easing antibiotic side effects in kids

NCT ID NCT05840588

First seen Nov 21, 2025 · Last updated Jun 19, 2026 · Updated 28 times

Summary

This study tested whether a probiotic called Bifidobacterium breve PRL2020 could reduce stomach issues like diarrhea in 121 children aged 3-12 who were taking amoxicillin antibiotics. The children took the probiotic alongside their antibiotic treatment. The goal was to see if it helped maintain healthy gut bacteria and eased symptoms.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Università di Urbino Carlo Bo

    Urbino, PU (Pesaro E Urbino), 61029, Italy

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Probiotic Bifidobacterium breve PRL2020 (Brevicillin®)

What this could lead to

If it works, this could offer a simple way to reduce stomach problems like diarrhea in children taking common antibiotics.

What could go wrong

This is a small, completed study with 121 children, and the results may not apply to all kids or antibiotics. The probiotic might not work for everyone.

Conditions

The condition(s) this trial relates to.

bacterial infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.