B ACUTE LYMPHOBLASTIC LEUKEMIA, PHILADELPHIA CHROMOSOME NEGATIVE
Clinical trials for B ACUTE LYMPHOBLASTIC LEUKEMIA, PHILADELPHIA CHROMOSOME NEGATIVE explained in plain language.
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New combo therapy aims to tame leukemia in older patients
Disease control Recruiting nowThis study tests a drug called inotuzumab ozogamicin, which delivers a toxin directly to leukemia cells, combined with low-intensity chemotherapy. It includes about 276 adults with acute lymphoblastic leukemia (ALL), especially those over 60 or unfit for standard treatment. The g…
Matched conditions: B ACUTE LYMPHOBLASTIC LEUKEMIA, PHILADELPHIA CHROMOSOME NEGATIVE
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 23, 2026 19:18 UTC
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New combo therapy shows promise for Hard-to-Treat leukemia
Disease control Recruiting nowThis phase II trial is testing a combination of two targeted drugs, inotuzumab ozogamicin and blinatumomab, with or without ponatinib, for adults with a type of leukemia called B-ALL. The study includes newly diagnosed older adults and those whose cancer has returned or not respo…
Matched conditions: B ACUTE LYMPHOBLASTIC LEUKEMIA, PHILADELPHIA CHROMOSOME NEGATIVE
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 22, 2026 11:55 UTC
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New combo therapy aims to wipe out leukemia in adults who Can't take standard treatment
Disease control Recruiting nowThis study tests a combination of chemotherapy drugs (DA-EPOCH) plus an enzyme called asparaginase (Rylaze) in adults newly diagnosed with a fast-growing blood cancer (Philadelphia chromosome-negative ALL). The goal is to see if this mix can kill more cancer cells and achieve dee…
Matched conditions: B ACUTE LYMPHOBLASTIC LEUKEMIA, PHILADELPHIA CHROMOSOME NEGATIVE
Phase: PHASE2 • Sponsor: University of Washington • Aim: Disease control
Last updated Jun 18, 2026 11:51 UTC
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New combo therapy aims to wipe out leukemia without lifelong drugs
Disease control Recruiting nowThis study tests a new treatment plan for people aged 15 to 65 with a type of blood cancer called B-cell acute lymphoblastic leukemia. The plan combines a reduced dose of chemotherapy with an immunotherapy drug called blinatumomab, followed by more chemo and possibly a stem cell …
Matched conditions: B ACUTE LYMPHOBLASTIC LEUKEMIA, PHILADELPHIA CHROMOSOME NEGATIVE
Phase: PHASE2 • Sponsor: The First Affiliated Hospital of Soochow University • Aim: Disease control
Last updated Jun 17, 2026 12:02 UTC
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New enzyme combo aims to boost leukemia treatment in High-Risk adults
Disease control Recruiting nowThis study tests whether a new form of the drug asparaginase (made from a different bacterium) can be safely combined with standard chemotherapy for high-risk adults aged 18–54 with newly diagnosed acute lymphoblastic leukemia or lymphoblastic lymphoma. The treatment aims to kill…
Matched conditions: B ACUTE LYMPHOBLASTIC LEUKEMIA, PHILADELPHIA CHROMOSOME NEGATIVE
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 16, 2026 12:52 UTC