ATOPIC DERMATITIS

This study tests an injection called ADSTEM for people with moderate to severe eczema (atopic dermatitis) that hasn't improved with standard creams or pills. About 286 adults aged 19 to 70 will receive either the study drug or a placebo to see if it safely reduces skin redness, i…

This study compares two non-steroid creams—tacrolimus and crisaborole—for treating mild to moderate eczema in people aged 2 to 20 years. Over 8 weeks, researchers will measure how well each cream controls skin redness, itching, and irritation, and track any side effects. The goal…

This study tests an investigational drug called MG-K10 in about 498 adults and teenagers (age 12+) with moderate-to-severe atopic dermatitis (eczema) that hasn't improved with standard creams. Participants will receive either MG-K10 or a placebo injection to see if it reduces ski…

This study tests whether removing Staphylococcus aureus bacteria from the skin can reduce eczema severity in 100 people aged 6 and older with moderate-to-severe atopic dermatitis. Participants will undergo a decolonization protocol, and researchers will measure changes in disease…

This study compares two steroid-free ointments—crisaborole and tacrolimus—for treating eczema in 148 Pakistani patients aged 2 and older. Both treatments aim to control symptoms like itching and redness without the side effects of steroids. Researchers will track skin improvement…

The ROOT study tests a personalized nutrition program for pregnant women. By analyzing genes and nutrients, the program creates custom diet plans to reduce risks of preterm birth, preeclampsia, and gestational diabetes. The study will enroll 500 women in North Carolina and compar…

This study looks at whether leaving the white, creamy substance (vernix caseosa) that covers newborns at birth on their skin can help prevent eczema (atopic dermatitis) during the first year of life. About 1,383 babies will either have the vernix left on or be cleaned as usual, a…

This early-stage study tests a new medicine called REGN20423 for the first time in humans. It will check the drug's safety, how the body handles it, and what dose might work best. The study includes 136 people: healthy volunteers and adults with atopic dermatitis (eczema). Resear…

This study tests a cream called roflumilast to see how well it reduces itching in people with mild to moderate eczema (atopic dermatitis). About 40 people aged 12 and older will use the cream daily for 4 weeks and report their itch levels through a phone app. The goal is to under…

This study tests a gel called VC005 on adults with mild to moderate atopic dermatitis (eczema). The goal is to see if it reduces skin redness, itching, and rash better than a gel with no active ingredient. About 120 participants will use the gel daily, and doctors will measure ch…

This early-stage study tests the safety of a new drug called IBI3033 in 16 adults with moderate-to-severe atopic dermatitis (eczema). Participants receive either the drug or a placebo over 12 weeks, and researchers monitor side effects, drug levels in the blood, and early signs o…

This study tests whether adding Urgo FilmoCream Eczema to standard steroid cream improves symptom relief for people with mild to moderate atopic dermatitis. About 44 adults with two similar eczema patches will compare one patch treated with steroid cream alone to the other treate…

This early-phase study tests whether a single dose of HXN5003 is safe and tolerable in 28 healthy adults aged 18-55. Researchers will monitor side effects, vital signs, and how the drug moves through the body. This is a first step toward developing a treatment for atopic dermatit…

This study tests whether a new moisturizing balm made with a seawater ingredient works as well as a leading brand for treating mild to moderate eczema in people aged 6 months to 70 years. The goal is to see if it can reduce symptoms like itching and improve quality of life, while…

This study looks at whether cutting back on salt can make eczema less severe. Forty adults will follow a low-salt diet for 24 weeks and take either salt tablets or a placebo to see how sodium affects their skin. Researchers will measure eczema severity, skin sodium levels, and re…

This study tests whether a newer cream (crisaborole) works as well as a standard cream (tacrolimus) for children aged 2–18 with mild to moderate eczema. About 66 kids will use one of the two creams twice daily for 28 days. The main goal is to see how many achieve clear or almost …

This study explores whether detailed eye images can help predict and classify inflammatory skin conditions like psoriasis and eczema. Researchers will take high-resolution photos of the eyes of 950 people (patients and healthy volunteers) and use artificial intelligence to find p…

This early-stage study looks at how taking VC005 tablets with or without food changes the drug levels in the blood. It involves 30 healthy adults aged 18 to 45. The results will help decide the best way to take this medicine in future studies for atopic dermatitis (eczema).

This study tests a grain-of-rice-sized microdevice that places tiny amounts of approved drugs directly into patches of psoriasis or eczema. The goal is to see if the device can safely predict how a person's skin will respond to standard treatments. Ten adults with these skin cond…

This study looks at how caring for a child with mild to moderate eczema (atopic dermatitis) affects a caregiver's work and family life. Researchers will ask 100 Canadian caregivers about missed work, reduced productivity, and family impact using questionnaires. The goal is to bet…

This study will test a new, gentle device that collects fluid from the skin of babies up to 6 months old. Researchers want to see if the device is comfortable and can measure chemical signals that may help explain why some babies develop eczema. The goal is to find early clues th…

This study will look at existing medical records from 20,000 people aged 12 and older in Italy who have psoriasis, atopic dermatitis, vitiligo, alopecia areata, or hidradenitis suppurativa. Researchers want to learn about the types of treatments patients receive, how their diseas…

This study will follow 50 Costa Rican adults with moderate-to-severe atopic dermatitis (eczema) who are already receiving advanced treatments like dupilumab or JAK inhibitors as part of their routine care. Researchers will collect data from regular doctor visits to see how sympto…

This study aims to create a standard method for collecting and analyzing skin oil (sebum) to find biomarkers for skin diseases like acne, eczema, and psoriasis. Researchers will study 200 participants, including healthy people and those with skin conditions, to see how skin oil c…