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Eye scans could reveal hidden skin disease risk

NCT ID NCT07434076

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Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
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Paused for now. It may or may not start again.
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Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
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Cancelled before anyone took part.

Expanded access (not trials)

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Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
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Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will take high-resolution photos of the eyes of 950 people with psoriasis, eczema, or hives, plus healthy volunteers. Using artificial intelligence, researchers aim to find eye patterns linked to these skin conditions. The goal is to create a noninvasive tool for earlier diagnosis and to predict related health risks like metabolic problems.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 950 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Mar 2026

An estimate. Start dates often move.

Expected to finish

May 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

As an exploratory cross-sectional study involving high-dimensional image-omics modeling, we plan to enlarge the sample size. We intend to recruit 200 cases each of psoriasis, atopic dermatitis, and urticaria, and 150 healthy controls. The dataset will be split into training and internal validation sets at an 8:2 ratio. An external independent validation cohort of 200 subjects is planned. The total sample size is therefore approximately 950 participants.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: For patients with inflammatory skin disease: Clinical diagnosis of one of the three target inflammatory skin diseases (psoriasis, atopic dermatitis, or urticaria). Age ≥ 18 and ≤ 65 years, any sex. Understands and signs informed consent. For healthy controls: Do not meet diagnostic criteria for any of the three inflammatory skin diseases above. Age ≥ 18 and ≤ 65 years, any sex. Understands and signs informed consent. Exclusion Criteria: For patients with inflammatory skin disease: Exclude any subject meeting any of the following: Refusal to undergo examinations. Presence of acute/active infectious ocular disease (e.g., viral keratoconjunctivitis). Corneal perforation or high-risk perforation where contact procedures cause severe photophobia, eye pain, inability to keep eyes open or fixate. Nystagmus or other conditions that prevent fixation. Pupillary non-dilation (e.g., posterior synechiae) that precludes fundus imaging. Severe eyelid lesions (e.g., marked swelling, ectropion, entropion) that prevent globe exposure. Participation in other clinical trials within the previous 3 months or concurrent participation in other interventional studies. * Healthy control - exclusion criteria Exclude any subject meeting any of the following: Presence of other skin diseases that could affect study assessments (e.g., atopic dermatitis, urticaria, scabies). Refusal to undergo examinations. Acute/active infectious ocular disease (e.g., viral keratoconjunctivitis). Corneal perforation or high-risk perforation that causes severe photophobia, eye pain, inability to keep eyes open or fixate during contact procedures. Nystagmus or other reasons preventing fixation. Pupillary non-dilation (e.g., posterior synechiae) that prevents fundus imaging. Participation in other clinical studies within the previous 3 months or currently participating in other clinical trials.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

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More trials for these conditions

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