APLASTIC ANEMIA

This study tests whether adding special 'veto' cells to a stem cell transplant can help donor cells grow in the body without causing severe graft-versus-host disease (GVHD). It includes 16 people aged 12-75 with various blood cancers or bone marrow failure. The veto cells are tre…

This study tested a modified approach to prevent and treat cytomegalovirus (CMV) infection in 153 people with blood cancers who had a donor stem cell transplant. The goal was to see if delaying or adjusting anti-CMV therapy could still keep patients safe while reducing unnecessar…

This study tests a bone marrow transplant method that avoids harsh drugs and radiation, which can worsen lung and liver disease or raise cancer risk in people with dyskeratosis congenita. About 40 participants with bone marrow failure will receive this gentler approach. The goal …

This study is checking how safe ATGAM is for people with moderate to severe aplastic anemia, a condition where the bone marrow doesn't make enough blood cells. Only one person is taking part, and they will be watched for 24 weeks to see if any side effects happen. The goal is to …

This study looks at whether adding methadone to the usual pain medicine (morphine) can better control severe mouth pain in children aged 6 to 18 getting a stem cell transplant. The mouth pain, called mucositis, is a common side effect of the chemotherapy given before transplant. …

This study follows people with aplastic anemia who previously received the drug romiplostim in earlier clinical trials. The goal is to see how well the treatment works over up to 5 years and to monitor any long-term side effects, such as new chromosome changes or blood cancers. A…