APLASTIC ANEMIA

This study tested a two-step stem cell transplant for people with blood cancers like leukemia and lymphoma. The approach uses low-dose chemo and radiation before a donor stem cell infusion, followed by drugs to prevent graft-versus-host disease. The goal was to control the cancer…

This study tested a drug called eltrombopag in 20 Chinese adults with severe aplastic anemia, a rare condition where the bone marrow stops making enough blood cells. Participants had not improved after standard treatments. The drug was given daily for up to a year, with the dose …

This study tested a new treatment for people with severe aplastic anemia, a rare condition where the bone marrow stops making enough blood cells. The treatment combined three drugs: rabbit antithymocyte globulin, cyclosporine, and levamisole. The goal was to see if this combinati…

This study tested a personalized geriatric optimization plan (GO!) in 30 patients over 60 receiving a stem cell transplant for blood cancers or bone marrow failure. The plan included tailored changes to diet, sleep, activity, and medications. The goal was to see if these changes …

This study tested whether adding luspatercept to standard cyclosporine treatment helps people with newly diagnosed non-severe aplastic anemia (a rare bone marrow failure condition) who do not yet need blood transfusions. The trial enrolled 58 adults and compared the combination t…

This study tested a combination of rabbit antithymocyte globulin (a drug that suppresses the immune system) and ciclosporin in 35 people with aplastic anemia, a condition where the bone marrow stops making enough blood cells. The goal was to see if this treatment could improve bl…

This study tested a two-step stem cell transplant for people with high-risk blood cancers like leukemia and lymphoma. First, patients got low-dose chemotherapy and radiation to prepare the body. Then, they received donor immune cells followed by donor stem cells to help destroy c…

This study tested a combined bone marrow and kidney transplant from a partially matched family donor for 10 people with both a serious blood disorder and chronic kidney disease. The goal was to treat both conditions with one donor, potentially reducing the need for lifelong anti-…

This study reviewed medical records of 13 Korean children with severe aplastic anemia, a condition where the bone marrow stops making enough blood cells. Researchers wanted to see if adding eltrombopag to standard immunosuppressive therapy was safe and effective over 6 months. Th…