AORTIC VALVE DISEASE
Clinical trials for AORTIC VALVE DISEASE explained in plain language.
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New heart valve trial offers hope without open surgery
Disease control ENROLLING_BY_INVITATIONThis study tests a new device called the Navitor TAVI system, which replaces a narrowed heart valve without open-heart surgery. It includes up to 1,500 people with severe aortic stenosis who are at low or intermediate risk for surgery. The goal is to see if the device is safe and…
Matched conditions: AORTIC VALVE DISEASE
Phase: NA • Sponsor: Abbott Medical Devices • Aim: Disease control
Last updated May 26, 2026 04:10 UTC
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New heart valve device shows promise for aortic stenosis patients
Disease control OngoingThis study is testing a new device called the DurAVR™ THV system for people with severe aortic stenosis, a condition where the heart's aortic valve becomes narrow and stiff. The study involves 40 participants who need a valve replacement and are eligible for a minimally invasive …
Matched conditions: AORTIC VALVE DISEASE
Phase: NA • Sponsor: Anteris Technologies Ltd. • Aim: Disease control
Last updated May 26, 2026 03:54 UTC
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New tiny heart valve gives hope to kids with aortic disease
Disease control OngoingThis study is testing a small mechanical heart valve (15mm) designed for children who need their aortic valve replaced. Researchers are following 20 kids for up to 5 years to see how safe and effective the valve is. The goal is to track serious side effects and how well the valve…
Matched conditions: AORTIC VALVE DISEASE
Sponsor: Abbott Medical Devices • Aim: Disease control
Last updated May 22, 2026 14:02 UTC
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New heart valve study tracks safety and performance in 190 patients
Disease control OngoingThis study looks at how safe and effective the Avalus Ultra heart valve is for people with aortic valve disease. About 190 participants will be followed for one year after surgery to check for complications and how well the valve works. The goal is to make sure the valve helps bl…
Matched conditions: AORTIC VALVE DISEASE
Phase: NA • Sponsor: Medtronic Cardiac Surgery • Aim: Disease control
Last updated May 20, 2026 11:54 UTC
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Common arthritis drug may delay heart valve surgery for millions
Disease control OngoingThis study tests whether colchicine, an anti-inflammatory medicine, can slow the worsening of aortic valve stenosis—a common heart valve condition. About 150 adults with moderate, symptom-free valve narrowing will take colchicine or a placebo for up to 2 years. The goal is to see…
Matched conditions: AORTIC VALVE DISEASE
Phase: PHASE3 • Sponsor: Radboud University Medical Center • Aim: Disease control
Last updated May 18, 2026 12:04 UTC
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Heart valve patients may go home in just 24 hours!
Symptom relief OngoingThis study looks at whether it is safe for people with narrowed heart valves to leave the hospital just 24 hours after a minimally invasive valve replacement (TAVI). Researchers will track 585 patients for serious problems like stroke, heart attack, or need for a pacemaker. The g…
Matched conditions: AORTIC VALVE DISEASE
Sponsor: Fundación EPIC • Aim: Symptom relief
Last updated May 26, 2026 03:57 UTC
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Scientists hunt for hidden genes behind deadly aortic aneurysms
Knowledge-focused OngoingThis study aims to find the genes that cause thoracic aortic aneurysms and other aortic valve diseases. Researchers will collect blood and tissue samples from 3000 people with these conditions, as well as their family members, to build a biorepository for genetic analysis. The go…
Matched conditions: AORTIC VALVE DISEASE
Sponsor: Yale University • Aim: Knowledge-focused
Last updated May 26, 2026 04:12 UTC
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Real-World study tracks aortic valve replacement outcomes
Knowledge-focused OngoingThis study followed 900 adults who had aortic valve replacement to see how safe and effective the procedure is in routine hospital care. Researchers tracked deaths from any cause and heart-related deaths. The goal is to understand real-world results beyond controlled clinical tri…
Matched conditions: AORTIC VALVE DISEASE
Sponsor: Seung-Jung Park • Aim: Knowledge-focused
Last updated May 20, 2026 11:54 UTC