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Heart valve mystery: scientists hunt for genetic clues in 1,000 patients

NCT ID NCT04149600

First seen Jun 11, 2026 · Last updated Jun 17, 2026 · Updated 2 times

Summary

This study collects tissue samples from 1,000 people having heart valve surgery to find genetic causes of calcific aortic valve disease. Researchers will compare normal and diseased tissue to understand why the disease develops. Participants must be at least 20 years old and have no prior valve replacement or certain heart conditions.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

Conditions

The condition(s) this trial relates to.

aortic aneurysm aortic disorder aortic valve calcification Aortic Valve Disease aortic valve disorder aortic valve insufficiency aortic valve stenosis Aortic Valve, Calcification of

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.