AORTIC ANEURYSM

This study is testing a new device called the NEXUS Aortic Arch Stent Graft System to treat serious conditions in the main artery near the heart, such as aneurysms, dissections, and ulcers. About 110 adults will receive the stent graft through a minimally invasive procedure. The …

This study tests a stent that doctors modify by hand to treat large bulges in the aorta (the body's main artery). The goal is to see if this less invasive approach is as safe and effective as traditional open surgery. About 80 people aged 50 and older with aneurysms in the chest …

This study tests a new tool called the Rapidlink device, used during open surgery to repair or replace major blood vessels in the chest. About 150 adults needing aortic surgery will take part. The goal is to see if the device is safe and works well, with follow-up for two years a…

This study explores whether a portable device that measures chest vibrations from heartbeats can diagnose aortic valve disease and aortic aneurysms. Researchers will compare readings from 180 adults with and without these conditions. The goal is to develop a non-invasive, easy-to…

This study tests a new guidance system called LumiGuide to see if it can reduce the amount of X-ray needed during a complex procedure to repair an aortic aneurysm. About 182 adults will be randomly assigned to receive the standard X-ray guidance or the new LumiGuide system. The m…

This study aims to understand how exercise affects the aorta in people with aortic aneurysm. Researchers will use special MRI scans during exercise to measure how the aorta stretches and responds. They will also test tissue samples from surgery to see how the aorta's physical pro…

This study is creating a large collection of blood, tissue, and health information from 15,000 people, including those with heart conditions like aortic aneurysm and heart failure, as well as healthy volunteers. The goal is to provide researchers with a valuable resource to bette…

This study tests whether 3D printed models of a patient's own diseased aorta can help surgeons plan aneurysm surgery more effectively. Ten adults with aortic aneurysms who need non-emergency surgery will have their CT scans turned into physical models. The main goal is to see if …

This study tests an AI software called Aorta AIM that automatically measures the aorta from CT scans. Researchers will compare its measurements to those made by expert doctors using existing scans from 250 adults in Brazil and the US. The goal is to see if the AI is accurate and …

This study is collecting health information from 5,000 people who have a genetic risk for heritable thoracic aortic disease (H-TAD), a condition that can cause dangerous bulges or tears in the aorta. Researchers want to learn how different gene changes affect the disease and what…

This study looks at the strength of the aorta (the main artery) in people with aortic disease compared to those without. Researchers want to see if certain patient traits are linked to a weaker aortic wall, which could help predict rupture risk. About 250 adults having heart surg…