AORTIC DISEASES

This study tests a new device called Encompass F2 that aims to protect the brain during a heart valve replacement procedure (TAVR). About 500 people getting TAVR will be randomly assigned to use this new device or standard care. The goal is to see if the device reduces brain inju…

This study follows 1,200 people who received Intervascular grafts or patches during surgery to repair or replace arteries in the neck, chest, or legs. Researchers will check how well the devices work over time, including how often they stay open, need reintervention, or cause inf…

This study tests a special catheter that uses sound waves (shockwaves) to break up calcium buildup in the leg arteries. This makes it easier for doctors to place a large stent in the aorta to treat aortic disease. The study will include 40 adults with severely calcified arteries …

This study tests a new tool called the Rapidlink device, used during open surgery to repair or replace major blood vessels in the chest. About 150 adults needing aortic surgery will take part. The goal is to see if the device is safe and works well, with follow-up for two years a…

This study tests a single-dose pain block against the standard method that uses a continuous catheter for pain relief after open abdominal surgery. About 14 adults having elective vascular surgery will take part. The goal is to see if the single-dose approach is safer, cheaper, a…

This study tests a new balloon device used during a heart valve replacement procedure (TAVI) for people with severe aortic stenosis. The main goal is to see if using this balloon before placing the new valve lowers the chance of developing heart rhythm problems. About 93 particip…

This study is collecting health information from 5,000 people who have a genetic risk for heritable thoracic aortic disease (H-TAD), a condition that can cause dangerous bulges or tears in the aorta. Researchers want to learn how different gene changes affect the disease and what…

This study aims to improve how we detect and understand heart disease using a new type of MRI that looks at the heart's microscopic structure. Researchers will compare these advanced scans with standard tests and blood work in 1,000 adults, both healthy volunteers and those with …