AORTIC ANEURYSM

This study tests a stent graft that doctors modify by hand to treat large bulges in the aorta (the body's main artery) that extend into the chest and belly. The goal is to see if this custom approach is safer and works as well as traditional open surgery. About 80 people aged 50 …

This study tests whether stent grafts that are modified by the surgeon to fit each patient's unique anatomy can safely treat aortic aneurysms. Thirty participants with aneurysms that are large, growing, or causing symptoms will receive the custom graft and be followed for five ye…

This study tests a new device called the NEXUS aortic arch stent graft system in 110 adults with serious conditions like aortic dissection or aneurysm affecting the aortic arch. The goal is to see if it is safe and effective at repairing the damaged area without major complicatio…

This study is testing a new device called Rapidlink that helps surgeons repair or replace blood vessels branching off the main artery (aorta) during open heart surgery. About 150 adults who need this type of surgery will take part. The goal is to see if the device is safe and wor…

This study explores whether kinocardiography (KCG), a portable device that measures chest vibrations from heartbeats, can diagnose aortic valve disease and thoracic aortic aneurysm. Researchers will compare KCG readings with standard imaging in 180 adults, including those with an…

This study tests a new guidance system called LumiGuide that uses light instead of X-rays during a complex aortic aneurysm repair procedure (FEVAR). The goal is to see if it reduces the time patients and doctors are exposed to radiation. About 182 adults needing this surgery will…

This study aims to find safe exercise levels for people with aortic aneurysm by using special MRI scans during exercise. Researchers will compare the scans with the physical properties of the aorta tissue. The goal is to help patients and doctors know how much exercise is safe.

This study looks at whether a special heart ultrasound measurement, called global longitudinal strain (GLS), can predict if a person will have trouble coming off the heart-lung machine during heart surgery. About 213 adults having planned heart surgery will have their hearts meas…

This study installs a 'black box' recording system in hybrid operating rooms to capture and analyze errors during vascular procedures. Researchers will study how teamwork, leadership, and the environment affect surgical performance and patient safety. The goal is to identify high…

This study tests an artificial intelligence (AI) software called Aorta AIM that automatically measures the aorta from CT scans. Researchers want to see if the AI is as accurate as expert doctors. About 250 adults who already had a chest or abdominal CT scan will participate, usin…

This study tracks 40 adults with aortic disease to see how their heart's shape and function change over a year after a minimally invasive aortic repair (EVAR). Researchers use MRI scans to measure heart muscle mass and other details at 6 and 12 months. The goal is to understand, …

This study looks at the strength of the aorta (the main artery) in people having heart surgery. Researchers want to find out why some aortas are weak and prone to tearing or bursting. They will compare tissue from patients with aortic disease to those without. The goal is to bett…

This study explores whether 3D printed models of a patient's own diseased aorta can help surgeons plan aneurysm surgery more effectively. Ten adults with thoracic or abdominal aortic aneurysms who are scheduled for non-emergency surgery will have their CT scans turned into physic…

This study is creating a large collection of blood, tissue, and health information from 15,000 people with and without heart conditions. The goal is to help researchers better understand diseases like aortic aneurysm, heart failure, and bicuspid aortic valve. Participants provide…

This study is gathering 5,000 people with certain gene changes that raise the risk of aortic disease (like aneurysms or dissections). Researchers will track their health over time to see how these genes affect the condition. The goal is to better predict and manage the disease, n…