ANASTOMOTIC LEAKAGE

This study compares using a reinforcement patch on surgical staplers versus standard staplers during stomach surgery (gastrojejunostomy) for gastric cancer. The goal is to see if the patch lowers the risk of leaks, bleeding, or narrowing at the connection site. About 382 patients…

This study looks at whether giving a drug called somatostatin along with a clear liquid diet for a week after rectal cancer surgery can prevent dangerous bowel leaks as well as a temporary stoma (a bag outside the body). About 72 adults with low or mid rectal cancer will be rando…

This study tests whether doing a colonoscopy 5 to 8 days after low colorectal cancer surgery can detect anastomotic leakage (a serious complication where the surgical connection leaks) earlier than standard monitoring. About 140 adults who had surgery for colorectal cancer will b…

This study tests if using a special vacuum device inside the body right after colorectal cancer surgery can prevent leaks where the intestine is reconnected. About 110 adults having surgery for colorectal cancer will either get the vacuum therapy or standard care. The main goal i…

This study compares two approaches during colorectal cancer surgery: leak testing (using a scope, air, and blue dye) versus no leak testing. The goal is to see if leak testing lowers the chance of a dangerous leak where the bowel is reconnected. About 264 adults having colorectal…

This study looks at a new way to reconnect the colon after surgery for cancer or diverticular disease. The goal is to see if using a single stapler instead of two can lower the risk of dangerous leaks at the connection point. About 500 adults having planned left-sided colon surge…