AMYLOIDOSIS CARDIAC

This study tests whether a special ultrasound treatment can improve blood flow and heart function in people with cardiac amyloidosis, a condition where abnormal proteins build up in the heart. Researchers will compare 70 participants with and without the disease, measuring change…

This study follows 200 adults with ATTR amyloidosis who are taking the drug tafamidis. Researchers will check every six months for heart rhythm problems that might need a pacemaker or defibrillator. The goal is to learn how often these issues occur and improve monitoring in routi…

This study looks at whether tiny particles released by cells into the blood, called extracellular vesicles, can help detect heart damage from ATTR amyloidosis earlier and less invasively. Researchers will compare these particles in 70 people with different stages of the disease a…

This study looks at 50 people with cardiac amyloidosis who are starting a new medication. Researchers want to see if advanced heart scans (ultrasound, MRI, and PET) can show why the disease keeps getting worse in about one-third of patients despite treatment. Participants will ha…

This study is creating a biobank and data registry for people with amyloidosis, a rare disease where abnormal proteins build up in organs. Researchers will collect blood, urine, and tissue samples along with medical information from 505 participants. The goal is to store these ma…

This study looks at heart tissue samples from 216 adults who already need a biopsy as part of their care. Researchers want to find unique molecular patterns for different heart conditions, like cardiomyopathy and heart transplant recovery. The goal is to improve how doctors diagn…