ALZHEIMER DISEASE (AD)

This study tests if infusions of cells from umbilical cord blood can improve cognitive function in people with mild-to-moderate Alzheimer's disease. Thirty participants will receive either a low dose, high dose, or a placebo (saline) infusion weekly for four weeks, plus a fifth i…

This study tests whether levetiracetam, a seizure medication, can prevent epileptic seizures in adults over 40 with Down syndrome who also have Alzheimer's disease. 120 participants will receive either the drug or a placebo for 96 weeks. The goal is to see if the drug can stop se…

This study tests whether daridorexant, a sleep medication, can help prevent Alzheimer's disease by clearing harmful proteins from the brain. It is open to 240 adults without dementia, even if they don't have sleep problems. Participants will take the drug or a placebo for a perio…

This observational study compares brain NAD levels in people with Alzheimer's disease and healthy older adults. Researchers will use a special MRI scan to measure NAD in the brain twice over eight months. The goal is to see if lower NAD is linked to Alzheimer's, which could guide…

This study follows 1,573 Canadians aged 50–90 with various types of dementia or normal memory to track how brain health changes over time. Participants complete memory tests, brain scans, and provide blood samples. The goal is to better understand different forms of dementia, not…

This study looks at whether a combination of genetic tests, blood markers, and data from wearable devices can predict early memory problems in people aged 55 and older who carry the ApoE4 gene, which raises Alzheimer's risk. Researchers will follow 100 participants for two years …