Alcohol use disorder
Clinical trials for Alcohol use disorder explained in plain language.
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Could a seizure drug curb alcohol withdrawal in trauma wards?
Disease control Stopped earlyThis trial tests whether valproate, a medication used for epilepsy, can help prevent or ease alcohol withdrawal symptoms in heavy drinkers admitted to trauma care. Participants receive standard treatment with lorazepam (a benzodiazepine) as needed, and some also get valproate. Th…
Matched conditions: ALCOHOL USE DISORDER
Phase 4 • Sponsor: CAMC Health System • Aim: Disease control
Last updated Aug 20, 2026 00:00 UTC
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Can a brain zapping headset curb relapse in addiction?
Disease control Stopped earlyThis study tests whether combining a gentle brain stimulation technique called tDCS with computer-based cognitive training can help people with stimulant or alcohol use disorders stay abstinent. Participants, who have already been abstinent for at least three weeks, will receive …
Matched conditions: ALCOHOL USE DISORDER
Sponsor: University of Minnesota • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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CBD shows promise for alcohol use disorder in early trial
Disease control Stopped earlyThis phase 2 trial tested whether cannabidiol (CBD), a non-psychoactive compound from cannabis, could help people with alcohol use disorder reduce their drinking. The study also looked at whether CBD could protect the brain and liver from alcohol's harmful effects. Only 10 people…
Matched conditions: ALCOHOL USE DISORDER
Phase 2 • Sponsor: Hôpital le Vinatier • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Can Brain-Training games rewire the mind to fight alcohol addiction?
Symptom relief Stopped earlyResearchers at the University of Florida are testing whether computerized cognitive training can help people with alcohol use disorder improve their memory, self-control, and thinking skills during inpatient treatment. Participants complete up to 12 sessions of adaptive brain-tra…
Matched conditions: ALCOHOL USE DISORDER
Sponsor: University of Florida • Aim: Symptom relief
Last updated Sep 18, 2026 00:00 UTC
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Can imagining future events and brain zaps ease pain and cravings?
Knowledge-focused Stopped earlyThis study looks at whether imagining positive future events (Episodic Future Thinking) and using low-intensity focused ultrasound on the brain can help people with both chronic pain and alcohol use disorder. Ten adults will try these interventions and report changes in pain, cra…
Matched conditions: ALCOHOL USE DISORDER
Sponsor: Kirstin M Gatchalian • Aim: Knowledge-focused
Last updated Sep 16, 2026 00:00 UTC
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Baclofen safety study halted early: what we learned
Knowledge-focused Stopped earlyThis study tracked 239 adults in France taking baclofen for alcohol use disorder. Researchers called participants monthly for a year to see how many stopped the drug due to side effects. The goal was to better understand which side effects are caused by baclofen versus other fact…
Matched conditions: ALCOHOL USE DISORDER
Phase 4 • Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC