ADVANCED MALIGNANT SOLID NEOPLASM
Clinical trials for ADVANCED MALIGNANT SOLID NEOPLASM explained in plain language.
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Experimental cocktail aims to reboot immune attack on tough cancers
Disease control TerminatedThis early-phase study tested a drug called plinabulin combined with radiation and immunotherapy in 19 people with advanced cancers (like lung, bladder, or melanoma) that had stopped responding to standard immunotherapy. The goal was to see if the combination was safe and could s…
Matched conditions: ADVANCED MALIGNANT SOLID NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 04:15 UTC
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Experimental cancer combo trial halted early
Disease control TerminatedThis study tested a combination of two immunotherapy drugs (BMS-986218 and nivolumab) plus precise radiation for people with advanced solid tumors that had spread. The goal was to see if this approach could help control the cancer and check for side effects. Only 13 people took p…
Matched conditions: ADVANCED MALIGNANT SOLID NEOPLASM
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 22, 2026 13:54 UTC
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Immunotherapy duo shows promise for HIV cancer patients
Disease control TerminatedThis early-stage study tested two immunotherapy drugs, ipilimumab and nivolumab, in 79 people with HIV who also had advanced solid tumors or Hodgkin lymphoma. The goal was to find the safest dose and see if the combination could shrink tumors. The trial was stopped early, but res…
Matched conditions: ADVANCED MALIGNANT SOLID NEOPLASM
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 20, 2026 11:54 UTC
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Cancer trial uses DNA tests to pick drugs, but stops early
Knowledge-focused TerminatedThis study tested a precision medicine approach for people with advanced cancers like breast, prostate, or pancreatic cancer. Researchers used genetic and protein tests to track how each person's cancer changed over time, then a team of experts recommended personalized drugs. The…
Matched conditions: ADVANCED MALIGNANT SOLID NEOPLASM
Phase: PHASE2 • Sponsor: OHSU Knight Cancer Institute • Aim: Knowledge-focused
Last updated May 26, 2026 04:14 UTC