ADRENOCORTICAL CARCINOMA

This early-phase trial tests a new treatment for people with advanced melanoma or other solid tumors that have spread. The treatment uses the patient's own immune cells, which are modified in a lab to recognize and attack cancer cells. The goal is to find a safe dose and see if t…

This study tests whether the immunotherapy drug dostarlimab works better than standard chemotherapy as the first treatment for people with advanced cancers that have specific genetic markers (dMMR/MSI). The cancers studied are rare types like pancreatic, stomach, and small bowel …

This study tests whether giving the drug pembrolizumab after standard radiation therapy is safe for people with advanced adrenocortical carcinoma (a rare adrenal gland cancer). The trial will enroll 12 participants and focus on tracking side effects. The goal is to see if this co…

This study is a registry that collects data from up to 1,000 people diagnosed with adrenocortical carcinoma, a rare cancer of the adrenal gland. The goal is to gather information on how the disease progresses and how different treatments work, so doctors can better understand wha…

This research study aims to discover new genes that may increase the risk of childhood cancer. Researchers will collect blood samples and health information from 1,500 people in families where cancer clusters. The goal is to build a registry and sample bank to help future diagnos…

This study aims to better understand how adrenal tumors develop and to evaluate new treatment options for adrenal cancer. Researchers will enroll 500 people who have an adrenal tumor seen on imaging. The goal is to improve care for patients with these rare tumors.