ACUTE PANCREATITIS

This study tests a single dose of a new drug called RABI-767, given via an endoscopic ultrasound injection near the pancreas, for people with predicted severe acute pancreatitis. About 36 participants will be randomly assigned to receive either RABI-767 plus standard care or stan…

This study tests a drug called CM4620 in children and young adults who develop pancreatitis (inflammation of the pancreas) after receiving a chemotherapy drug called asparaginase for leukemia or lymphoma. The goal is to see if CM4620 is safe and can reduce the severity of the pan…

This study tests whether transplanting healthy gut bacteria (FMT) can prevent serious infections in people with moderate to severe acute pancreatitis. About 80 adults will receive either FMT or a placebo. The goal is to see if FMT lowers the risk of infected pancreatic tissue, se…

This study looks at whether removing the gallbladder early (during the hospital stay for pancreatitis) or waiting about a month after recovery leads to better outcomes. About 134 adults with severe or moderately severe pancreatitis caused by gallstones will be randomly assigned t…

This study is testing if a single dose of an existing anti-inflammatory drug, infliximab, can help control the severe inflammation caused by acute pancreatitis. Adults recently hospitalized with the condition will receive either a low dose, a high dose, or a placebo infusion. The…

This study tests if transplanting healthy gut bacteria (fecal microbiota transplantation) can prevent infections like pneumonia and infected pancreatic tissue in people with severe acute pancreatitis. About 150 adults aged 18-75 with moderate to severe disease will receive the tr…

This study tests a special freezing tool (cryoprobe) to remove dead tissue from the pancreas in people with a serious complication of pancreatitis. The standard method uses tools like forceps, but the dead tissue can be sticky and hard to grab. The cryoprobe freezes the tissue so…

This study collects blood, tissue, and health information from up to 20,000 people with pancreas diseases like pancreatic cancer or pancreatitis. Researchers will use these samples and data to better understand these conditions and develop better screening methods in the future. …

This study follows 800 people who recently had acute pancreatitis to see who develops diabetes and why. Participants are monitored for 3 years with tests and surveys, but no new treatments are given. The goal is to better understand the link between pancreatitis and diabetes.

This study is a registry that will collect information from up to 1,000 adults who receive standard endoscopic treatment for fluid collections caused by pancreatitis. The goal is to see how well the treatment works and what outcomes patients experience. No new treatments are bein…

This study follows 800 people who recently had acute pancreatitis to see if a continuous glucose monitor (CGM) can predict who will develop diabetes or pre-diabetes. Researchers will track participants for 36 months using CGM and other tests. The goal is to improve how doctors mo…

This study watches 500 adults with acute pancreatitis to see how often blood clots form in key belly veins (splenic, portal, or superior mesenteric). Researchers will check if these clots are linked to more severe pancreatitis and complications like infected fluid collections. No…