Acute pain
Clinical trials for Acute pain explained in plain language.
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Pain relief combo falls short: early trial halted
Symptom relief Stopped earlyThis study tested whether adding baclofen (a muscle relaxant) to buprenorphine (a painkiller) could improve pain relief in 19 healthy volunteers. Participants received either a placebo or baclofen alongside buprenorphine and then underwent heat-based pain tests. The trial was ter…
Matched conditions: ACUTE PAIN
Phase 2/3 • Sponsor: University of Alabama at Birmingham • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Small study measures lidocaine levels in Post-Surgery pain control
Knowledge-focused Stopped earlyThis study aimed to measure how much lidocaine is in the blood over time when given as a weight-based infusion for pain after major surgery. It planned to include 40 adults, but only 7 took part before the study was stopped early. The goal was to better understand dosing, not to …
Matched conditions: ACUTE PAIN
Sponsor: University of Alberta • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Heart surgery pain study seeks answers
Knowledge-focused Stopped earlyThis study aimed to find out how many people experience short-term and long-term pain after a specific type of heart surgery called one-stage hybrid arrhythmia ablation. Researchers surveyed patients who had the procedure at UZ Brussels to see what factors, like medications or ge…
Matched conditions: ACUTE PAIN
Sponsor: Universitair Ziekenhuis Brussel • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC