ACUTE-ON-CHRONIC LIVER FAILURE

This study tests a new drug called F573 in people with liver injury or liver failure. The goal is to see if it is safe and how it affects the body. About 97 adults will take part, and half will get the drug while the other half gets a placebo. The study focuses on safety and does…

This study tests a new blood-filtering method (DPCAS+LPE) for people with sudden liver failure and sepsis. About 192 adults will receive either this new treatment or standard plasma exchange. The goal is to see if the new method lowers death rates at 4 and 12 weeks and reduces in…

This study looks at how well liver transplantation works for people with severe acute-on-chronic liver failure (ACLF). Researchers will track 3,000 adults with cirrhosis who are listed for a transplant to see who survives and how to improve outcomes. The goal is to find the best …

This study tests whether adding a blood-filtering device called CytoSorb to standard care helps people with acute-on-chronic liver failure. It involves 20 adults whose liver suddenly worsens, causing high bilirubin and confusion. The device aims to remove toxins from the blood ov…

This study tests whether a blood-filtering device called DPMAS can improve immune function in people with acute-on-chronic liver failure. The device removes toxins and inflammatory substances from the blood. Researchers will compare 40 intensive care patients who receive either s…

This study reviews medical records of 446 people with hepatitis B-related liver failure who received stem cell therapy. Researchers want to find out why some patients improved while others did not. The goal is to identify factors that affect treatment success, so future patients …

This study is a large registry that collects data on how a blood-filtering device called CytoSorb is used in real-world intensive care settings. It will include up to 3,000 critically ill patients with conditions like septic shock, severe lung injury, or liver failure. The goal i…