ACUTE-ON-CHRONIC LIVER FAILURE
Clinical trials for ACUTE-ON-CHRONIC LIVER FAILURE explained in plain language.
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New device aims to filter toxins from blood in liver crisis
Disease control CompletedThis study tested a new medical device called MEX-CD1 in 11 adults with acute-on-chronic liver failure (ACLF), a sudden worsening of long-term liver disease. The device works like a dialysis machine to remove excess iron from the blood. Researchers wanted to see if it is safe and…
Matched conditions: ACUTE-ON-CHRONIC LIVER FAILURE
Phase: NA • Sponsor: Mexbrain • Aim: Disease control
Last updated May 19, 2026 11:46 UTC
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New blood test may reduce transfusions and complications in liver failure bleeding
Disease control CompletedThis study tested whether a special blood test (ROTEM) can better guide blood transfusions in people with acute-on-chronic liver failure who are bleeding. 262 participants were randomly assigned to receive transfusions based on either the ROTEM test or standard blood tests. The g…
Matched conditions: ACUTE-ON-CHRONIC LIVER FAILURE
Phase: NA • Sponsor: Post Graduate Institute of Medical Education and Research, Chandigarh • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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Healthy volunteers help test new liver Drug's safety
Knowledge-focused CompletedThis early-stage study tested a new drug called G1090N in 52 healthy adults to measure how the body processes it and to check for side effects. The goal was not to treat any disease, but to gather important safety and dosing information before testing it in patients with liver pr…
Matched conditions: ACUTE-ON-CHRONIC LIVER FAILURE
Phase: PHASE1 • Sponsor: Genfit • Aim: Knowledge-focused
Last updated May 26, 2026 05:30 UTC
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Study seeks best fluid strategy for liver patients with sepsis
Knowledge-focused CompletedThis study looked at 350 adults with liver cirrhosis and sepsis-induced low blood pressure to find the best way to decide how much fluid to give. The goal was to see which method helps reach a safe blood pressure without causing fluid overload. The findings may improve care for t…
Matched conditions: ACUTE-ON-CHRONIC LIVER FAILURE
Sponsor: Post Graduate Institute of Medical Education and Research, Chandigarh • Aim: Knowledge-focused
Last updated May 26, 2026 05:23 UTC