Acute-on-chronic liver failure
Clinical trials for Acute-on-chronic liver failure explained in plain language.
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Experimental liver drug shows early promise but trial cut short
Disease control Stopped earlyThis early study tested a drug called VS-01 in 15 adults with acute-on-chronic liver failure (a sudden worsening of liver function) and fluid buildup in the belly. Participants received either VS-01 plus standard care or standard care alone. The trial was terminated early, so we …
Matched conditions: ACUTE-ON-CHRONIC LIVER FAILURE
Phase 2 • Sponsor: Genfit • Aim: Disease control
Last updated Jul 25, 2026 00:00 UTC
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Blood filtering treatment tested for sudden liver failure
Disease control Stopped earlyThis study tested a blood filtering procedure called plasma exchange using a 5% albumin solution in people with acute-on-chronic liver failure (ACLF), a sudden worsening of chronic liver disease. The trial enrolled 274 high-risk patients across the US, Canada, and Europe, compari…
Matched conditions: ACUTE-ON-CHRONIC LIVER FAILURE
Phase 3 • Sponsor: Instituto Grifols, S.A. • Aim: Disease control
Last updated Jun 27, 2026 13:03 UTC