ACL
Clinical trials for ACL explained in plain language.
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Knee surgery for Over-50s: does a specialized ACL technique match younger Patients' results?
Disease control Recruiting nowThis study compares outcomes of a specific ACL reconstruction technique, called over-the-top with lateral extra-articular tenodesis (LET), in patients over 50 years old versus those under 30. The technique uses the patient's own hamstring tendons and adds an extra procedure to st…
Matched conditions: ACL
Sponsor: Stefano Zaffagnini • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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Could a Parent's hamstring tendon rebuild a Child's torn ACL?
Disease control Recruiting nowThis trial is testing whether using a hamstring tendon from a parent can safely and effectively reconstruct a torn anterior cruciate ligament (ACL) in children and teenagers whose bones are still growing. The study will enroll 40 patients aged 8 to 17 with ACL tears that need sur…
Matched conditions: ACL
Sponsor: Maidstone & Tunbridge Wells NHS Trust • Aim: Disease control
Last updated Jul 31, 2026 00:00 UTC
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Second-Time ACL repair: new technique shows promise for knee stability
Disease control Recruiting nowThis study looks at how well a particular revision ACL surgery works over the long term. The technique uses a donor Achilles tendon and an extra stitch on the outside of the knee. Researchers will check knee function, stability, and arthritis development in 59 people who had this…
Matched conditions: ACL
Sponsor: Stefano Zaffagnini • Aim: Disease control
Last updated Jul 04, 2026 00:00 UTC
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Special treadmill training may help ACL recovery
Symptom relief Recruiting nowThis study tests whether walking on a split-belt treadmill (where each leg moves at a different speed) can improve how the knee loads weight after ACL reconstruction. Nine people who had ACL surgery within the past 10 months will be randomly assigned to one of two training groups…
Matched conditions: ACL
Sponsor: University of Michigan • Aim: Symptom relief
Last updated Sep 17, 2026 00:00 UTC
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Can electrical stimulation or vibration boost leg strength after ACL surgery?
Symptom relief Recruiting nowThis study looks at whether neuromuscular electrical stimulation (NMES) or vibration can help people who have had anterior cruciate ligament (ACL) reconstruction regain strength in their quadriceps (thigh muscle). The researchers want to see if these treatments reduce muscle inhi…
Matched conditions: ACL
Sponsor: University of Wisconsin, Madison • Aim: Symptom relief
Last updated Sep 12, 2026 00:00 UTC
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Vibration and cold may replace opioids after ACL surgery
Symptom relief Recruiting nowThis study tests a device called VibraCool that uses cooling and vibration to reduce pain after ACL knee surgery. The goal is to see if it can lower pain scores and help people stop taking opioid pain pills sooner. About 130 adults who had ACL reconstruction will use the device a…
Matched conditions: ACL
Sponsor: Columbia University • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC