ACL
Clinical trials for ACL explained in plain language.
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New ACL graft material shows promise in small trial
Disease control CompletedThis study tested a new material called OrthoPure XT for repairing torn knee ligaments (ACL) in 10 people. Researchers measured pain, knee function, and activity levels using surveys and MRI scans. The goal was to see if the material works well for patients who cannot use their o…
Matched conditions: ACL
Phase: NA • Sponsor: Istituto Ortopedico Rizzoli • Aim: Disease control
Last updated May 26, 2026 09:00 UTC
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New nerve block approach may cut opioid need after ACL repair
Symptom relief CompletedThis study tested whether adding genicular nerve blocks to standard pain treatment helps people who have ACL knee surgery. 192 adults were randomly assigned to receive either the extra nerve blocks or usual care. The goal was to see if the blocks reduce opioid painkiller use and …
Matched conditions: ACL
Phase: PHASE4 • Sponsor: Hospital for Special Surgery, New York • Aim: Symptom relief
Last updated May 14, 2026 12:06 UTC
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Treadmill training shows promise for ACL recovery
Knowledge-focused CompletedThis study looked at whether a 20-minute treadmill walk could temporarily improve how the knee bears weight after ACL reconstruction. 32 people who had ACL surgery within the past 10 months took part. The goal was to see if different walking patterns on the treadmill could lead t…
Matched conditions: ACL
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated May 19, 2026 11:59 UTC