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Scientists uncover muscle secrets behind ACL injuries in athletes

NCT ID NCT07608575

Knowledge-focused Sponsor: Universiti Sains Malaysia Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
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Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

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Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
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First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how trunk and leg muscles work together to load the ACL during a single-leg landing in 40 male college athletes. Researchers used motion capture and muscle models to estimate ACL force. The goal was to find muscle patterns that could help prevent ACL injuries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

40 people

The number who actually took part.

Started

Jun 2024

Finished

Jul 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consisted of forty collegiate male athletes aged 19 to 25 years who participated in sports involving frequent jumping and landing movements. All participants had a minimum of three years of competitive experience and trained at least twice per week. Individuals with a history of major lower limb or back injury requiring surgery, current musculoskeletal injury, or medical conditions limiting maximal physical effort were excluded. All participants provided written informed consent prior to participation.

Ages

19 to 25 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male collegiate athletes aged 19-25 years * Minimum of 3 years of competitive experience in jump-landing sports (e.g., volleyball, basketball, netball) * Training frequency of at least twice per week * No history of back or lower limb injury Exclusion Criteria: * History of major lower limb or back injury requiring surgery * Any medical condition preventing maximal physical effort * Current musculoskeletal pain or injury affecting movement performance

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACL

Contacts and locations

Locations

  • School of Mechanical Engineering, Universiti Sains Malaysia

    Nibong Tebal, Pulau Pinang, Malaysia

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