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Can electrical stimulation or vibration boost leg strength after ACL surgery?

NCT ID NCT07674784

Symptom relief Sponsor: University of Wisconsin, Madison Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 30, 2026 · Last updated Sep 11, 2026 · Updated 5 times

Summary

This study looks at whether neuromuscular electrical stimulation (NMES) or vibration can help people who have had anterior cruciate ligament (ACL) reconstruction regain strength in their quadriceps (thigh muscle). The researchers want to see if these treatments reduce muscle inhibition and improve strength. The study involves 22 participants who are 2 to 4 months post-surgery and will be followed for 2 to 3 weeks.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
neuromuscular electrical stimulation (NMES) and vibration
What this could lead to
If effective, these treatments could help people recover quadriceps strength more quickly after ACL surgery.
What could go wrong
This is a small, early-stage study with only 22 participants, so results may not apply to everyone. The treatments may not work better than standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 22 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Have undergone ACLR within the previous 4 months * Are at least 2 months post-ACLR Exclusion Criteria: * A history of ACLR on both legs * Since the most recent ACLR: * secondary lower extremity surgery * leg or foot fracture * Unable to walk without an assistive device * Pain of greater than 5/10 during quadriceps strengthening exercises with the surgical limb * Cannot achieve 90 degrees of knee flexion with the surgical limb * People with contraindications to NMES * Anyone who had a previous skin reaction to NMES or attempted but could not tolerate NMES * Peripheral neuropathy or other neurological conditions

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACL

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • UW Health

    RECRUITING

    Madison, Wisconsin, 53706, United States

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