Urinary system disorder
MONDO:0002118A disease involving the renal system.
Also known as: disease of renal system, disease or disorder of renal system, disease, urinary tract, disease, urologic, disease, urological, diseases, urinary tract, diseases, urologic, diseases, urological
5523 clinical trials for this condition and its sub-types, 72 tagged with Urinary system disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Urinary system disorder
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Kidney disorder 223 trials · 4,032 incl. sub-types
57 sub-types
- Chronic kidney disease 1,091 trials · 1,566 incl. sub-types Sub-types →
- Kidney failure 236 trials · 1,389 incl. sub-types Sub-types →
- Kidney neoplasm 59 trials · 860 incl. sub-types Sub-types →
- Nephritis 16 trials · 503 incl. sub-types Sub-types →
- Glomerular disorder 9 trials · 481 incl. sub-types Sub-types →
- Inherited kidney disorder 1 trial · 317 incl. sub-types Sub-types →
- Nephrolithiasis 252 trials · 254 incl. sub-types Sub-types →
- Proteinuria 65 trials · 137 incl. sub-types Sub-types →
- Impaired renal function disease 109 trials · 129 incl. sub-types Sub-types →
- Cystic kidney disease 8 trials · 87 incl. sub-types Sub-types →
- Nephrosis 0 trials · 71 incl. sub-types Sub-types →
- Renal infectious disease 16 trials · 64 incl. sub-types Sub-types →
- Renal tubule disorder 1 trial · 47 incl. sub-types Sub-types →
- Diabetes insipidus 33 trials · 37 incl. sub-types Sub-types →
- Renal tubular transport disease 0 trials · 17 incl. sub-types Sub-types →
- Hydronephrosis 7 trials · 9 incl. sub-types Sub-types →
- Stricture or kinking of ureter 9 trials
- Hypertensive nephropathy 8 trials Sub-types →
- Nephrocalcinosis 7 trials · 8 incl. sub-types Sub-types →
- Renal artery disease 3 trials · 7 incl. sub-types Sub-types →
- Fetal lower urinary tract obstruction 0 trials · 6 incl. sub-types Sub-types →
- Congenital primary megaureter 5 trials Sub-types →
- Renal hypertension 0 trials · 4 incl. sub-types Sub-types →
- Distal renal tubular acidosis 3 trials Sub-types →
- Exstrophy-epispadias complex 1 trial · 3 incl. sub-types Sub-types →
- Acute tubulointerstitial nephritis 2 trials
- Kidney cortex necrosis 2 trials
- IgG4-related kidney disease 1 trial
- Anuria 1 trial
- Crush syndrome 1 trial
- Obstructive nephropathy 1 trial
- Orthostatic proteinuria 1 trial
- Renal hypoplasia 1 trial Sub-types →
- Renal nutcracker syndrome 1 trial
- Arnold stickler bourne syndrome 0 trials
- C1q nephropathy 0 trials
- X-linked diffuse leiomyomatosis-Alport syndrome 0 trials Sub-types →
- Atheroembolism of kidney 0 trials
- Atypical Fanconi syndrome-neonatal hyperinsulinism syndrome 0 trials
- Autosomal dominant progressive nephropathy with hypertension 0 trials
- Congenital megacalycosis 0 trials Sub-types →
- Congenital renal artery stenosis 0 trials
- Duplication of urethra 0 trials
- Idiopathic non-lupus full-house nephropathy 0 trials
- Kidney cortex disease 0 trials
- Kidney hypertrophy 0 trials
- Kidney papillary necrosis 0 trials Sub-types →
- Lachiewicz sibley syndrome 0 trials
- Neonatal renal venous thrombosis 0 trials
- Non-syndromic supernumerary kidneys 0 trials
- Oligomeganephronia 0 trials
- Perinephritis 0 trials
- Pyonephrosis 0 trials
- Renal aminoaciduria 0 trials
- Renal dysplasia 0 trials Sub-types →
- Renal tubular dysgenesis 0 trials Sub-types →
- Tubulointerstitial nephritis and uveitis syndrome 0 trials
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Urinary system neoplasm 21 trials · 1,690 incl. sub-types
8 sub-types
- Malignant urinary system neoplasm 75 trials · 1,664 incl. sub-types Sub-types →
- Kidney neoplasm 59 trials · 860 incl. sub-types Sub-types →
- Urinary bladder neoplasm 65 trials · 699 incl. sub-types Sub-types →
- Urothelial neoplasm 2 trials · 693 incl. sub-types Sub-types →
- Benign urinary system neoplasm 50 trials · 62 incl. sub-types Sub-types →
- Ureter neoplasm 2 trials · 34 incl. sub-types Sub-types →
- Urethra neoplasm 3 trials · 31 incl. sub-types Sub-types →
- Prostate phyllodes tumor 0 trials Sub-types →
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Urinary bladder disorder 24 trials · 1,152 incl. sub-types
17 sub-types
- Urinary bladder neoplasm 65 trials · 699 incl. sub-types Sub-types →
- Overactive bladder 168 trials
- Female stress incontinence 137 trials
- Cystitis 12 trials · 72 incl. sub-types Sub-types →
- Ureterolithiasis 49 trials
- Bladder neck obstruction 12 trials
- Hinman syndrome 5 trials
- Bladder calculus 5 trials Sub-types →
- Vesicoureteral reflux 5 trials Sub-types →
- Detrusor sphincter dyssynergia 3 trials
- Urinary schistosomiasis 3 trials
- Low compliance bladder 2 trials
- Postcholecystectomy syndrome 1 trial
- Bladder diverticulum 0 trials Sub-types →
- Disorder of neck of urinary bladder 0 trials Sub-types →
- Ureterocele 0 trials
- Urinary bladder tuberculosis 0 trials
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Urolithiasis 119 trials · 312 incl. sub-types
2 sub-types
- Nephrolithiasis 252 trials · 254 incl. sub-types Sub-types →
- Lower urinary tract calculus 0 trials · 5 incl. sub-types Sub-types →
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Urinary tract infection 156 trials · 250 incl. sub-types
5 sub-types
- Bacterial urinary tract infection 55 trials · 81 incl. sub-types Sub-types →
- Renal infectious disease 16 trials · 64 incl. sub-types Sub-types →
- Trichomonas vaginitis urogenital infection 7 trials Sub-types →
- Urinary schistosomiasis 3 trials
- Pyoureter 0 trials
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Ureteral disorder 2 trials · 95 incl. sub-types
8 sub-types
- Ureterolithiasis 49 trials
- Ureter neoplasm 2 trials · 34 incl. sub-types Sub-types →
- Ureteral obstruction 9 trials
- Vesicoureteral reflux 5 trials Sub-types →
- Pyoureter 0 trials
- Ureter tuberculosis 0 trials
- Ureteritis 0 trials
- Ureterocele 0 trials
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Urethral disorder 1 trial · 70 incl. sub-types
10 sub-types
- Urethra neoplasm 3 trials · 31 incl. sub-types Sub-types →
- Urethral obstruction 3 trials · 26 incl. sub-types Sub-types →
- Urethritis 5 trials · 6 incl. sub-types Sub-types →
- Urethral syndrome 4 trials
- Urethral intrinsic sphincter deficiency 3 trials
- Fibroepithelial polyp of urethra 0 trials
- Prolapse of urethra 0 trials
- Urethral calculus 0 trials
- Urethral false passage 0 trials
- Urethral gland abscess 0 trials
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Urinary tract obstruction 12 trials · 27 incl. sub-types
2 sub-types
- Hydronephrosis 7 trials · 9 incl. sub-types Sub-types →
- Ureteral obstruction 9 trials
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Bacteriuria 11 trials
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Idiopathic hypercalciuria 3 trials
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Paraneoplastic renal syndrome 0 trials · 3 incl. sub-types
1 sub-type
- Oncogenic osteomalacia 3 trials
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Congenital urachal anomaly 0 trials
4 sub-types
- Patent urachus 0 trials
- Urachal cyst 0 trials
- Urachal diverticulum 0 trials
- Urachal sinus 0 trials
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Hypercalciuria, absorptive, 1 0 trials
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Hypercalciuria, absorptive, 2 0 trials
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Hyperglycinuria 0 trials
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Megacystis-megaureter syndrome 0 trials
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Meningitis-retention syndrome 0 trials
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Postorgasmic illness syndrome 0 trials
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Pyuria 0 trials
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Urothelial hyperplasia 0 trials
2 sub-types
- Flat urothelial hyperplasia 0 trials
- Papillary urothelial hyperplasia 0 trials
Most studied deeper sub-types
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Which laser frequency works best for prostate surgery?
Disease control CompletedThis trial compares three different laser frequency settings (40, 50, and 60 Hz) used during a procedure called HoLEP, which treats enlarged prostates causing bothersome urinary symptoms. Men aged 18-89 undergoing HoLEP will be randomly assigned to one of the laser settings on th…
Sponsor: Northwestern University • Aim: Disease control
Last updated Aug 22, 2026 00:00 UTC
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New drug combo shows promise for kidney disease in small trial
Disease control CompletedThis study tested whether adding the drug atrasentan to standard care (including SGLT2 inhibitors) can reduce protein in the urine of people with IgA nephropathy, a kidney disease. 54 adults with biopsy-confirmed IgA nephropathy participated. The main goal was to see if atrasenta…
Phase 2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jul 22, 2026 00:00 UTC
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New registry tracks artificial sphincter success for female incontinence
Disease control CompletedThis registry follows 180 women receiving an artificial urinary sphincter for stress incontinence caused by a weak sphincter. Researchers measure how many become dry (using no pads or just one light pad) and how long that dryness lasts over 5 years. Participants also report on se…
Sponsor: European Association of Urology Research Foundation • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New antibody drug shows promise for kidney disease
Disease control CompletedThis Phase 2 trial tested a drug called felzartamab in 54 adults with IgA nephropathy, a kidney disease that can lead to kidney failure. The drug targets immune cells to reduce protein leakage in urine, a sign of kidney damage. The study compared felzartamab to a placebo to see i…
Phase 2 • Sponsor: HI-Bio, A Biogen Company • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Could efgartigimod tame lupus nephritis? early trial hints at hope
Disease control CompletedThis phase 2 study tested the drug efgartigimod in 73 Chinese patients with active lupus nephritis, a serious kidney complication of lupus. Participants received either the drug or a placebo by IV infusion over 24 weeks. The main goal was to see if the drug could reduce protein i…
Phase 2 • Sponsor: argenx • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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New tube system could make dialysis access easier for kidney patients
Disease control CompletedThis study tested a new device called the FLEX System that creates a connection between an artery and a vein (AV fistula) using a tube inserted through the skin, instead of surgery. The goal was to see if this method is safe and works well for people with chronic kidney disease w…
Sponsor: C. R. Bard • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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No-Catheter bladder test shows promise in small study
Diagnosis CompletedThis study tested a new wireless device called the Glean Urodynamics System (GUS) that measures bladder pressure without a catheter. Thirty-eight adults with urinary symptoms used the device after a standard test. The goal was to see if the device is safe, easy to use, and more c…
Sponsor: Bright Uro • Aim: Diagnosis
Last updated Jun 27, 2026 08:05 UTC
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Smart blood pressure monitoring may shield kidneys during robotic surgery
Prevention CompletedThis trial tests whether a software tool called the hypotension prediction index (HPI) can help prevent acute kidney injury after robotic-assisted urologic surgery. The tool uses arterial pressure data to forecast drops in blood pressure during the operation, allowing doctors to …
Sponsor: Ewha Womans University Mokdong Hospital • Aim: Prevention
Last updated Sep 10, 2026 00:00 UTC
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Cow colostrum may shield kids from recurrent UTIs
Prevention CompletedThis study tested whether a supplement made from bovine colostrum (the first milk from cows) can prevent repeated urinary tract infections (UTIs) in children. Sixty children with a history of recurrent UTIs took part. The goal was to see if this natural prebiotic could reduce the…
Phase 2 • Sponsor: Ain Shams University • Aim: Prevention
Last updated Jun 27, 2026 08:08 UTC
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Could a phone app help parents of kids with special needs thrive?
Symptom relief CompletedThis trial tests a 12-week smartphone-based program called PACT, which combines acceptance and commitment training with positive parenting advice, for parents of children with special health care needs. The goal is to see if it can improve parents' mental well-being, psychologica…
Sponsor: Chinese University of Hong Kong • Aim: Symptom relief
Last updated Aug 13, 2026 00:00 UTC
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Magnetic stent removal spares kids from anesthesia
Symptom relief CompletedThis study tested a special ureteral stent with a magnetic end in 67 children with urinary tract problems or kidney transplants. The goal was to see if the stent could be removed without general anesthesia, using a magnetic catheter instead. The approach aims to make the removal …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Scientists create first tools to measure recurrent UTI burden
Knowledge-focused CompletedThis study aimed to develop and test two new questionnaires for people with recurrent urinary tract infections (UTIs). The Recurrent UTI Symptom Scale measures symptom severity, while the Recurrent UTI Impact Questionnaire looks at how the condition affects daily life, work, and …
Sponsor: University of Reading • Aim: Knowledge-focused
Last updated Aug 07, 2026 00:00 UTC
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Virtual doctor visits could cut wait times for urology patients in rural nigeria
Knowledge-focused CompletedThis study tested whether telemedicine could help people in rural Nigeria get urology care faster. 220 adults were split into two groups: one had a standard in-person consultation, the other a virtual consultation with a urologist. Researchers measured how long it took to see a s…
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Bowel troubles may slow recovery after prostate surgery
Knowledge-focused CompletedThis study looked at 120 men who had HoLEP surgery for an enlarged prostate. Researchers wanted to see if bowel problems before surgery made recovery harder. Patients filled out questionnaires about bowel and urinary symptoms before and after surgery. The goal was to learn how bo…
Sponsor: Northwestern University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC
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Nurse training cuts infection risk in kidney stone surgery
Knowledge-focused CompletedThis study tested a teaching program to improve nurses' knowledge and practice of infection control for patients having a procedure called percutaneous nephrolithotomy (PCNL) to remove kidney stones. Thirty nurses who care for these patients took part. The goal was to see if the …
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Emergency CT scans for kidney stones: what did 1,500 patients reveal?
Knowledge-focused CompletedThis study looked at 1,500 people who came to the emergency room with symptoms of a kidney stone and got a CT scan within 24 hours. Researchers wanted to know how many actually had a stone, where it was, and how big. They also checked whether having a fast CT scan changed how qui…
Sponsor: Region Skane • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:29 UTC