TRIM22-related inflammatory bowel disease

This study tests whether oral vancomycin, an antibiotic, can help children aged 6-15 with inflammatory bowel disease (IBD), especially types linked to liver problems. About 140 kids will either get vancomycin plus standard care or standard care alone for up to a year. Researchers…

This early-phase study tests a new treatment called ICG318 CAR-T for people with inflammatory bowel disease (IBD) that hasn't improved with standard therapies. The treatment uses a patient's own immune cells, modified in a lab to target and calm the overactive immune response cau…

This study tests if xylitol, a common sweetener, can safely clear C. difficile bacteria from the gut in people with inflammatory bowel disease (IBD). About 99 adults with mild or inactive IBD will take either a low or high dose of xylitol or a placebo for four weeks. Researchers …

This study tests whether neurofeedback — a type of brain training using real-time brainwave feedback — can reduce musculoskeletal pain in people with chronic inflammatory bowel disease (IBD). Eighty adults with IBD and persistent pain will be randomly assigned to either 8 session…

This study is exploring whether a rapid, non-invasive stool test can help monitor inflammatory bowel disease (IBD) in children. The test uses a technology called differential mobility spectrometry (DMS) to analyze the molecular profile of stool samples. Researchers will compare t…

This study looks at a new way to control inflammation during flare-ups of Crohn's disease and ulcerative colitis. Researchers will take blood samples from 30 adults with severe IBD and test whether oxygen microbubbles can reprogram immune cells (monocytes) to produce fewer inflam…

This study looks at how weight and body mass index (BMI) change in people with inflammatory bowel disease (IBD) who are treated with biologic drugs. Researchers will track weight monthly and see if higher BMI leads to higher drug doses and costs. The goal is to understand the fin…

This study will follow 83 adults with inflammatory bowel disease (IBD) at Assiut University Hospitals in Egypt to see if anemia can predict worse outcomes like hospitalizations. Anemia is common in IBD, but its role as a predictor is not well studied in this population. Researche…

This study looks at how obesity influences treatment response in 120 adults with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. Researchers will track whether obese patients respond differently to standard therapies, especially biologics. The …

This study will check if certain blood cell measurements (platelet count, size, and shape) are linked to how active inflammatory bowel disease (IBD) is. Researchers will compare these blood test results with standard disease activity scores in 84 adults with IBD. The goal is to s…

This study will check how common Helicobacter pylori infection is in 100 adults with inflammatory bowel disease (Crohn's or colitis) at the Guadeloupe hospital. Researchers will take extra stomach biopsies during routine endoscopy to study the stomach's bacteria. The goal is to s…

This study compares a newer imaging method called TXI with standard dye-based imaging during colonoscopies in people with inflammatory bowel disease (IBD). The goal is to see which method better detects precancerous changes that can lead to bowel cancer. About 242 adults with IBD…

This study will use a detailed heart ultrasound technique called speckle tracking to look for early signs of heart trouble in 100 adults with inflammatory bowel disease (IBD). Researchers want to see if this method can catch heart changes before they become serious and how those …