Tinnitus

This early-phase study is testing whether stem cell therapies and experimental drugs can help repair inner ear damage in people with hearing loss or tinnitus. Researchers will monitor 120 adults over time using hearing tests and symptom surveys. The goal is to see if these regene…

This study was designed to test whether an oral drug called SPI-1005 could prevent hearing loss and ringing in the ears caused by platinum-based chemotherapy. It was planned for adults with advanced lung or head and neck cancer. The study was withdrawn before enrolling any partic…

Researchers are testing whether a highly absorbable form of curcumin, the main compound in turmeric, can reduce the bothersome ringing or buzzing of subjective tinnitus. The study enrolls adults whose tinnitus comes from sensorineural hearing loss, confirmed by a routine hearing …

This study looks at whether changes in brain waves can objectively measure tinnitus improvement after using a non-invasive device. The device delivers sound through headphones and mild electrical pulses to the tongue. Twenty-four adults with chronic tinnitus will use the device d…

This pilot study tests a compounded DMSO-based ear drops and cream for adults with bothersome tinnitus linked to long-COVID or post-COVID-19 vaccine injury. Twenty participants who have not improved with at least two prior treatments will use the ear drops every 4 days and apply …

This study tests whether online group counseling sessions can help people with chronic tinnitus. Researchers want to see if e-health works as well as traditional in-person sessions. 150 adults with subjective, chronic tinnitus will participate. The main goal is to measure changes…

This study is testing whether hearing aids alone or hearing aids with a tinnitus masker can improve hearing and reduce tinnitus symptoms in adults with hearing loss and tinnitus. One hundred participants will wear hearing aids for 6 months, with the masker turned on after 3 month…

This study aimed to test a closed-loop sound therapy for people with chronic tinnitus (ringing in the ears) or hyperacusis (sensitivity to sound). The therapy was designed to retrain the brain's response to sounds. However, the trial was withdrawn before any participants were enr…

This study tests whether common migraine medications can reduce the impact of sudden tinnitus (ringing in the ears) in 100 adults aged 25 to 85. Participants receive the drugs and complete questionnaires about their symptoms, plus brain scans to look for changes. The goal is to f…

This study tests whether donepezil, a drug used for dementia, can help people with chronic tinnitus (ringing in the ears). 70 adults with long-term tinnitus received either donepezil or a placebo for 3 months. Researchers measured changes in tinnitus severity using standard quest…

This study tests two simple, drug-free treatments for chronic tinnitus (ringing in the ears) that hasn't improved with standard medical care. 45 adults will be split into three groups: one gets 10 sessions of mild electrical stimulation to a nerve in the ear, another does specifi…

This study, run by Apple and the University of Michigan, tracks headphone and environmental sound exposure in 300,000 US adults using iPhones and Apple Watches. Participants answer surveys and take hearing tests through the Research app. The goal is to understand how everyday sou…