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Could migraine pills silence ringing ears? new trial investigates

NCT ID NCT06799169

Symptom relief Sponsor: University of California, Irvine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether common migraine medications can reduce the impact of sudden tinnitus (ringing in the ears) in 100 adults aged 25 to 85. Participants receive the drugs and complete questionnaires about their symptoms, plus brain scans to look for changes. The goal is to find a new way to ease tinnitus distress, since no FDA-approved drug currently exists for this condition.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with mild to moderate tinnitus. * Male or female between the ages of 25 to 85 years. * Subjects must be compliant with the medication and attend study visits. * Must be able to read and write in the English language to provide consent. Exclusion Criteria: * Pregnancy will result in automatic exclusion from the study. Rule out of pregnancy will be done by urine pregnancy test to confirm the situation for all women who are of childbearing potential. * Subjects with a history of an adverse reaction to medication being prescribed. * Subjects suffering from a medical condition or have a history that may be concerning to the investigator's clinical opinion. * All contraindications for the medications that prevent subjects from randomization will be considered as exclusion criteria.

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Conditions

The condition(s) this trial relates to.

migraine without aura tinnitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Tinnitus

Contacts and locations

Locations

  • University of California, Irvine Medical Center ENT Clinic (Pavilion 2)

    Orange, California, 92868, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.