Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Could nicotine gum silence the ringing in your ears?

NCT ID NCT07772089

Symptom relief Sponsor: San Diego State University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 19, 2026 · Last updated Sep 04, 2026 · Updated 2 times

Summary

This trial asks whether a single piece of nicotine gum can reduce the loudness of tinnitus—the phantom ringing or buzzing in the ears—in non-smoking adults who have had chronic tinnitus for at least six months. Participants will chew either a 4 mg nicotine gum or a flavor-matched placebo gum in two separate sessions, without knowing which is which. The study measures changes in tinnitus loudness and the ability to focus on relevant sounds, comparing the nicotine session to the placebo session.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Nicotine polacrilex gum (4 mg)
What this could lead to
If effective, a single dose of nicotine gum might offer a temporary way to quiet the phantom ringing of tinnitus and improve focus on sounds.
What could go wrong
This is an early, small trial (29 people) testing only one dose. Nicotine can have side effects and is addictive, and the effect may not last or may not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1/2

Runs two stages together: safety and dose first, then whether the treatment works.

Participants

29 people

The number who actually took part.

Started

Mar 2026

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Non-smoking adult, defined as fewer than 100 cigarettes in a lifetime and none in the past year, with a Fagerstrom Test for Nicotine Dependence score of 2 or less and a negative urinary cotinine test * Chronic subjective tinnitus of at least 6 months' duration Exclusion Criteria: * Current or recent tobacco or nicotine use * Pregnancy or breastfeeding * Unstable cardiovascular disease * Any condition precluding the psychoacoustic tasks

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Chronic subjective tinnitus are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

tinnitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic subjective tinnitus Tinnitus

Contacts and locations

Locations

  • San Diego State University

    San Diego, California, 92182, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.