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Promising sound therapy trial for ringing ears pulled before it began

NCT ID NCT07302373

Symptom relief Sponsor: Massachusetts Eye and Ear Infirmary Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled This study
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study aimed to test a closed-loop sound therapy for people with chronic tinnitus (ringing in the ears) or hyperacusis (sensitivity to sound). The therapy was designed to retrain the brain's response to sounds. However, the trial was withdrawn before any participants were enrolled, so no results are available.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Sound therapy (closed-loop and placebo)
What this could lead to
If it had worked, this could have pointed toward a new sound-based treatment to reduce tinnitus and sound sensitivity.
What could go wrong
The trial was withdrawn before enrolling anyone, so we have no data on whether the therapy is safe or effective. It remains an early idea with no proof yet.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Expected to start

Sep 2022

An estimate. Start dates often move.

Expected to finish

Sep 2023

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 89 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Normal audiometric thresholds * Subjects with tinnitus will have self-reported chronic tinnitus that has persisted for the duration of at least 6 months * Subjects with hyperacusis will have a clinical diagnosis of hyperacusis and/or self-reported sound tolerance complaints that have persisted for the duration of at least 6 months Exclusion Criteria: * Conductive hearing loss (as assessed by audiologist) * Active otologic disease (as assessed by audiologist) * Significant cognitive decline (Montreal Cognitive Assessment score \> 25)

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Conditions

The condition(s) this trial relates to.

hyperacusis tinnitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hyperacusis Tinnitus

More trials for these conditions

Other studies related to the condition(s) this trial covers.