Tibia fracture

Researchers are comparing two timings for flap surgery in adults with severe open fractures or dislocations below the knee. One group receives a flap within 72 hours of injury, while the other follows the standard timing used at each hospital. The trial measures death, amputation…

This pilot trial tests whether a low-cost negative pressure wound therapy (NPWT) system is a practical alternative to standard dressings for severe open tibia fractures in a low-resource setting. Researchers will randomly assign 66 adults with Gustilo-Anderson type IIIb open tibi…

This trial asks whether formal outpatient physical therapy leads to better recovery than a self-guided home exercise program for people who had surgery for a broken thigh or shin bone. Participants will be randomly assigned to one of the two programs and followed for a year with …

This phase 4 trial will test whether tranexamic acid (TXA), a drug that reduces bleeding, can safely lower blood loss in 200 orthopedic trauma patients who are on anticoagulants (blood thinners). Participants will have surgery for broken leg or thigh bones. The study compares tho…

This trial tests a new type of nail made from magnesium and titanium to fix broken leg or arm bones. The nail is designed to provide strong support while part of it gradually dissolves over time. Researchers will compare it to standard metal nails in 160 adults to see if it is ju…

This study tests a safety bundle—staff training, checklists, and audits—to prevent surgical site infections after emergency C-sections and open leg fracture repairs in Ethiopia. About 1,000 patients at public hospitals will be followed for 2 years to measure infection rates and d…

Researchers are testing whether a structured rehabilitation program works better than usual physiotherapy for adults recovering from surgery to fix a traumatic tibial fracture. The program guides progression through four phases using set clinical and functional criteria, while re…

This study tests if using a floor pedal bike at home helps people recover from leg fractures and ankle injuries. Twenty adults with these injuries will get a bike at their first post-surgery visit and be asked to use it regularly. Researchers will track their physical activity an…

This study compares two surgical methods for fixing a broken shinbone (tibia). One technique enters above the kneecap, the other from the side of the kneecap. Researchers will measure knee function, pain, and recovery in 40 adults aged 18-60. The goal is to find which approach le…

This early study tests whether applying nitroglycerin ointment (a medicine that widens blood vessels) to surgical wounds during high-risk leg surgeries can improve blood flow and reduce complications like infection or wound separation. Fifteen adults undergoing specific ankle, he…

This study tests whether a structured, supervised exercise program can help adults recover from serious leg fractures. About 40 people who had surgery for a broken thigh or shin bone will either do the exercise program or get usual care. The main goal is to see if the program is …