Sleep disorder
MONDO:0100081A change from the patient's baseline sleeping pattern, in the hours slept and/or an alteration/dysfunction in the stages of sleep.
Also known as: disturbances, sleep, sleep disturbance, sleep disturbances, parasomnia
2089 clinical trials for this condition and its sub-types, 507 tagged with Sleep disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Sleep disorder
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Sleep-wake disorder 179 trials · 1,049 incl. sub-types
12 sub-types
- Sleep apnea syndrome 214 trials · 600 incl. sub-types Sub-types →
- Circadian rhythm sleep disorder 103 trials · 138 incl. sub-types Sub-types →
- Narcolepsy 38 trials · 57 incl. sub-types Sub-types →
- Bruxism 56 trials
- Hypersomnia 24 trials · 50 incl. sub-types Sub-types →
- REM sleep behavior disorder 48 trials Sub-types →
- Sleep disorder, initiating and maintaining sleep 18 trials
- Periodic limb movement disorder 2 trials
- Autoimmune encephalopathy with parasomnia and obstructive sleep apnea 0 trials
- Autosomal dominant cerebellar ataxia, deafness and narcolepsy 0 trials
- Hereditary sensory neuropathy-deafness-dementia syndrome 0 trials
- Recurrent hypersomnia 0 trials Sub-types →
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Insomnia 822 trials · 826 incl. sub-types
1 sub-type
- Fatal familial insomnia 4 trials
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Parasomnia, sleepwalking type 4 trials
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Parasomnia, sleep terrors type 2 trials
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Nocturnal paroxysmal dystonia 0 trials
Most studied deeper sub-types
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Migraine drug ajovy put to the test for better sleep
Disease control Stopped earlyThis study looked at whether fremanezumab (Ajovy), an FDA-approved monthly injection for migraine prevention, could also improve sleep in people with migraines. Researchers planned to track 22 participants over 4 months, comparing their migraine days and sleep quality before and …
Phase 4 • Sponsor: Beth Israel Deaconess Medical Center • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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Quick fix for nightmares? 10-Minute therapy tested in military clinics
Symptom relief Stopped earlyThis study tested a short, 10-minute therapy called Nightmare Rescripting and Rehearsal to help people with recurring distressing nightmares. It was designed for use by primary care staff, not mental health specialists, and included sleep hygiene education for all participants. T…
Sponsor: David Moss • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Sleep therapy tested for Alzheimer's brain fog
Symptom relief Stopped earlyThis study tested a behavioral program using bright light therapy and sleep coaching to improve sleep and thinking in older adults with mild cognitive impairment or mild Alzheimer's. Only 15 people were enrolled before the study was stopped early. The goal was to see if the progr…
Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Calm app tested on stressed doctors – but study cut short
Symptom relief Stopped earlyThis study looked at whether using the Calm meditation app could help medical residents and fellows at Banner University Medical Center Phoenix feel less stressed, anxious, or burned out during the COVID-19 pandemic. Only 7 people signed up, and the study was stopped early, so we…
Sponsor: University of Arizona • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Can a restless legs drug ease opioid withdrawal?
Symptom relief Stopped earlyThis study tested whether pramipexole (Mirapex), a drug for restless legs syndrome, could also reduce symptoms of opioid withdrawal in people with opioid use disorder. The trial planned to enroll 75 adults but was terminated early. Researchers measured changes in restless legs se…
Phase 2/3 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Can zapping the ear during a nap boost memory?
Knowledge-focused Stopped earlyResearchers at the University of California, San Francisco are studying whether stimulating the vagus nerve through the ear during a nap can improve memory. The trial enrolls healthy adults aged 18 to 64 who nap regularly. Participants receive either active stimulation or a sham …
Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Sep 17, 2026 00:00 UTC
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Mental health study aims to uncover Long-Term heart risks
Knowledge-focused Stopped earlyThis study followed 167 adults with mental health issues like anxiety, depression, or sleep problems who visited their primary care doctor. Researchers used health conversations and a blood test to track lifestyle changes and heart disease risks over up to 20 years. The goal was …
Sponsor: Region Skane • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC