Secondary pulmonary hemosiderosis

This trial tests whether a four-step ladder made with goat milk formula helps children aged 1 to 5 with cow's milk allergy build tolerance to milk better than the standard cow's milk ladder. Both ladders start with baked goods and progress to plain milk over 12 weeks, with each s…

This trial tests whether a digital rehabilitation programme called I-IMPACT can be a practical alternative to traditional centre-based pulmonary rehabilitation for adults with interstitial lung disease (ILD). The study will compare the two approaches, focusing on feasibility—such…

This trial tests whether giving children with cow's milk allergy tiny, increasing amounts of milk each day can help them tolerate it. Infants aged 6 to 18 months with a confirmed allergy will be randomly assigned to receive oral immunotherapy for 1-1.5 years or to avoid milk as u…

This study compares a new extensively hydrolyzed formula (eHF) to a standard eHF in full-term infants diagnosed with cow's milk protein allergy (CMPA). The goal is to see if the new formula supports healthy growth and is as safe and well-tolerated as the standard one. Infants age…

This study will test if a smart pill bottle cap, called FORTISKAP™, helps people with serious lung diseases like pulmonary fibrosis, sarcoidosis, and pulmonary hypertension take their oral medications more consistently. About 100 participants will either use the smart cap or rece…

This study tests whether a special anti-regurgitation formula, made from extensively hydrolysed casein, is safe and well-tolerated in infants with cow's milk protein allergy (CMPA). About 55 babies aged 1 to 9 months will take part. The formula is given in a controlled food chall…

This study tests a new extensively hydrolyzed formula for infants aged 0-5 months with mild-to-moderate cow's milk protein allergy (CMPA). The formula is designed to relieve symptoms like skin rashes, stomach issues, and breathing problems. Over 28 days, researchers will compare …

Researchers at Mayo Clinic are testing an investigational radioactive tracer called 68Ga-FAPI-46 to see how it distributes in the lungs of people with interstitial lung disease. About 10 participants with a clinical diagnosis of ILD and lung abnormalities on a recent CT scan rece…

Researchers are testing a noninvasive MRI technique that uses inhaled hyperpolarized xenon gas to measure lung function in adults with interstitial lung disease, pulmonary hypertension, and systemic sclerosis. The study includes about 51 participants, including healthy volunteers…

This study tests whether a partially digested whey formula can help doctors tell the difference between a non-allergic milk intolerance and a true cow's milk protein allergy in babies. Infants aged 1 to 6 months with digestive symptoms will receive the special formula. The goal i…

This study tests two special formulas—amino acid formula (AAF) and extensively hydrolyzed formula (eHF)—in 360 infants aged 0-6 months with suspected cow's milk protein allergy. Babies will receive one formula for at least 2 weeks, and doctors will check if symptoms like diarrhea…

This study tests whether a virtual reality (VR) program that guides slow, controlled breathing and arm exercises can help people with interstitial lung disease (ILD) manage symptoms like breathlessness and fatigue. Participants will either use a VR headset or follow printed instr…

This study tests whether a supervised Clinical Pilates program can improve physical function, breathing, and quality of life in 58 adults with interstitial lung disease (ILD). Participants are randomly assigned to either Pilates sessions plus standard care or standard care alone.…

Interstitial lung diseases cause lung scarring and stiffness, making it hard to breathe. This study will test whether an 8-week pulmonary rehabilitation program—including walking, cycling, and strength exercises—can improve diaphragm function, exercise ability, and quality of lif…

People with interstitial lung disease (ILD) can suddenly get much worse, but it is hard to tell if the cause is a lung flare-up or a blood clot in the lungs (pulmonary embolism). This observational study will follow 70 adults with ILD who come to the hospital with worsening breat…

This study will track 427 adults with interstitial lung disease (ILD) who need a bronchoscopy as part of their care. Researchers want to see how often complications happen within 30 days after the procedure. The goal is to better understand the risks so doctors can make safer cho…

This study will use a procedure called bronchoalveolar lavage (BAL) to collect fluid from the lungs of 66 adults with suspected interstitial lung disease (ILD). The fluid will be analyzed to identify specific inflammatory cells, which may help doctors distinguish between differen…

This study will observe 160 infants aged 1 to 12 months who have cow's milk protein allergy and are fed an amino acid-based formula. Researchers will measure weight, length, and head growth over time to see if the formula supports healthy development. The goal is to gather inform…