Lung rehab may strengthen breathing muscles in scarred lung disease
NCT ID NCT07205627
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
Interstitial lung diseases cause lung scarring and stiffness, making it hard to breathe. This study will test whether an 8-week pulmonary rehabilitation program—including walking, cycling, and strength exercises—can improve diaphragm function, exercise ability, and quality of life. Twenty adults with stable interstitial lung disease will participate at a hospital in Guadalajara, Mexico.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- pulmonary rehabilitation program (aerobic and strength training)
- What this could lead to
- If successful, this could show that pulmonary rehab improves breathing muscle function and daily life for people with interstitial lung disease.
- What could go wrong
- This is a very small, early study with only 20 participants and no control group, so results may not apply broadly. The program requires supervised sessions, which may be hard for some to attend.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2025
An estimate. Start dates often move.
- Expected to finish
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Dec 2025
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years. * Confirmed diagnosis of interstitial lung disease (ILD) by pulmonology and imaging criteria. * Clinically stable for at least 4 weeks prior to enrollment (no exacerbations or hospitalizations). * Able to perform pulmonary rehabilitation and functional tests safely, as determined by medical evaluation. * Willing and able to provide written informed consent. Exclusion Criteria: * Acute exacerbation of ILD or respiratory infection within the last 4 weeks. * Severe comorbidities limiting participation (e.g., unstable cardiac disease, uncontrolled hypertension, recent myocardial infarction \< 3 months). * Advanced neuromuscular disease or musculoskeletal limitation that prevents exercise training. * Cognitive impairment or psychiatric condition interfering with protocol adherence. * Pregnancy or breastfeeding
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Department of Physical Rehabilitation at the Civil Hospital of Guadalajara
Guadalajara, Jalisco, 44280, Mexico