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Retinal disorder
MONDO:0005283Any disease or disorder of the retina.
Also known as: eye disease of retina, retina eye disease, retinopathy
963 clinical trials for this condition and its sub-types, 89 tagged with Retinal disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Retinal disorder
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Retinal degeneration 41 trials · 576 incl. sub-types
6 sub-types
- Inherited retinal dystrophy 41 trials · 513 incl. sub-types Sub-types →
- Macular degeneration 212 trials · 429 incl. sub-types Sub-types →
- Retinoschisis 5 trials · 6 incl. sub-types Sub-types →
- Peripheral retinal degeneration 1 trial · 2 incl. sub-types Sub-types →
- Cone dystrophy 1, X-linked 0 trials
- Cone dystrophy 5, X-linked 0 trials
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Retinal vascular disorder 9 trials · 324 incl. sub-types
12 sub-types
- Diabetic retinopathy 148 trials · 260 incl. sub-types Sub-types →
- Retinal vascular occlusion 0 trials · 53 incl. sub-types Sub-types →
- Exudative vitreoretinopathy 1 trial · 35 incl. sub-types Sub-types →
- Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations 3 trials
- Retinal telangiectasia 0 trials · 2 incl. sub-types Sub-types →
- Retinal vasculitis 2 trials
- Retinal hemangioblastoma 1 trial Sub-types →
- Retinal microaneurysm 1 trial
- Arteriosclerotic retinopathy 0 trials
- Familial retinal arterial macroaneurysm 0 trials
- Perifoveal exudative vascular anomalous complex 0 trials
- Vasoproliferative tumor of retina 0 trials
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Inherited vitreoretinopathy 0 trials · 58 incl. sub-types
5 sub-types
- Vitreoretinal degeneration 0 trials · 45 incl. sub-types Sub-types →
- Congenital vitreoretinal dysplasia 0 trials · 9 incl. sub-types Sub-types →
- Vitreous detachment 5 trials
- NDP-related vitreoretinopathy 0 trials Sub-types →
- TSPAN12-related vitreoretinopathy 0 trials Sub-types →
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Retinal detachment 28 trials · 52 incl. sub-types
2 sub-types
- Rhegmatogenous retinal detachment 23 trials Sub-types →
- Retinal perforation 18 trials
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Retina neoplasm 2 trials · 36 incl. sub-types
5 sub-types
- Retinal cancer 2 trials · 35 incl. sub-types Sub-types →
- Retinal cell neoplasm 0 trials · 34 incl. sub-types Sub-types →
- Benign neoplasm of retina 0 trials · 1 incl. sub-types Sub-types →
- Retinal capillary malformation 0 trials
- Retinal neuroblastoma 0 trials
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Retinal edema 1 trial · 29 incl. sub-types
1 sub-type
- Macular retinal edema 20 trials · 28 incl. sub-types Sub-types →
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Macular holes 19 trials
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Night blindness 5 trials · 10 incl. sub-types
3 sub-types
- Congenital stationary night blindness 2 trials · 5 incl. sub-types Sub-types →
- Abnormal threshold of rods 0 trials
- Acquired night blindness 0 trials
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Retinitis 1 trial · 10 incl. sub-types
5 sub-types
- Optic papillitis 5 trials Sub-types →
- Cytomegalovirus retinitis 2 trials
- Retinal vasculitis 2 trials
- Histoplasmosis retinitis 1 trial
- Acute retinal necrosis syndrome 0 trials
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Central serous chorioretinopathy 8 trials
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Proliferative vitreoretinopathy 7 trials
1 sub-type
- CAPN5-related vitreoretinopathy 0 trials
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Achromatopsia 4 trials · 6 incl. sub-types
6 sub-types
- Blue cone monochromacy 2 trials
- Achromatopsia 7 1 trial
- Achromatopsia 2 0 trials
- Achromatopsia 3 0 trials
- Achromatopsia 4 0 trials
- Achromatopsia 6 0 trials
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Retinal ciliopathy 0 trials · 2 incl. sub-types
9 sub-types
- Leber congenital amaurosis 10 2 trials
- Leber congenital amaurosis with early-onset deafness 0 trials
- Cone-rod dystrophy 16 0 trials
- Retinitis pigmentosa 23 0 trials
- Retinitis pigmentosa 51 0 trials
- Retinitis pigmentosa 55 0 trials
- Retinitis pigmentosa 64 0 trials
- Retinitis pigmentosa 74 0 trials
- Retinitis pigmentosa 80 0 trials
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Hypertensive retinopathy 1 trial
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Iris hypoplasia with glaucoma 1 trial
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Retinal ischemia 1 trial
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1 sub-type
- Neuroretinitis 0 trials
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Eales disease 0 trials
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Acute macular neuroretinopathy 0 trials
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Angioid streaks 0 trials
1 sub-type
- Angioid streaks of choroid 0 trials
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Autoimmune retinopathy 0 trials
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Bradyopsia 0 trials
2 sub-types
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Cancer-associated retinopathy 0 trials
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Isolated chorioretinal dystrophy 0 trials
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Isolated foveal hypoplasia 0 trials
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Melanoma associated retinopathy 0 trials
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Myopic macular degeneration 0 trials
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Persistent placoid maculopathy 0 trials
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Rubeosis iridis 0 trials
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Torpedo maculopathy 0 trials
Most studied deeper sub-types
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One-Time gene injection aims to restore sight in rare childhood blindness
Cure CompletedThis trial tests a gene therapy for people with a rare inherited eye disease called Leber congenital amaurosis, caused by mutations in the RPE65 gene. A harmless virus is used to deliver a working copy of the gene into cells under the retina. The goal is to restore vision with a …
Phase 1 • Sponsor: University of Pennsylvania • Aim: Cure
Last updated Jul 19, 2026 00:00 UTC
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Can a contact lens improve clarity during retinal surgery?
Disease control CompletedThis trial tests whether a modified soft contact lens placed on the cornea during vitrectomy, a surgery for retinal disease, keeps the surgical view clearer than the standard method of intermittent saline irrigation. Researchers randomly assign 46 participants to receive either t…
Sponsor: Northwest University First Hospital (Xi'an No.1 Hospital) • Aim: Disease control
Last updated Sep 10, 2026 00:00 UTC
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New eye injection shows promise for rare Blindness-Causing gene mutation
Disease control CompletedThis early-stage study tested the safety of a new drug called VP-001, given as an injection into the eye, for people with a rare genetic eye disease (PRPF31 mutation) that causes vision loss. Six participants aged 12 and older received multiple doses. The main goal was to check f…
Phase 1 • Sponsor: PYC Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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New eye drug could save sight for millions with diabetes
Disease control CompletedThis study tested an eye injection called tarcocimab in 255 people with diabetic retinopathy, a diabetes complication that can damage vision. Participants received either the drug or a sham (fake) injection. The goal was to see if the drug improves the severity of the disease and…
Phase 3 • Sponsor: Kodiak Sciences Inc • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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Experimental pill targets toxic fat buildup in rare genetic disease
Disease control CompletedThis study tested an oral drug called ADX-629 in 8 people with Sjögren-Larsson syndrome, a rare inherited disorder that causes harmful fatty substances to build up in the skin, brain, and eyes. The main goals were to see if the drug is safe and can reduce these fatty aldehydes. P…
Phase 1/2 • Sponsor: University of Nebraska • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Refillable eye implant could replace monthly shots for diabetic eye disease
Disease control CompletedThis phase 3 trial tested a small, refillable implant placed in the eye that continuously releases the drug ranibizumab to control diabetic retinopathy. The study enrolled 174 people with moderate-to-severe non-proliferative diabetic retinopathy but without swelling in the center…
Phase 3 • Sponsor: Hoffmann-La Roche • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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New hope for rare eye disease: personalized drug schedule shows promise
Disease control CompletedThis study tested a personalized treatment plan using the drug brolucizumab for people with a specific eye condition called polypoidal choroidal vasculopathy (PCV). The goal was to see if adjusting the treatment schedule based on each person's needs could maintain or improve visi…
Phase 3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Eye drug dosing showdown: can fewer injections still control wet AMD?
Disease control CompletedThis study compared two different dosing schedules of brolucizumab (Beovu) in 52 people with wet age-related macular degeneration (AMD) who had not responded well to previous treatment. Participants received the drug as an eye injection either on a fixed schedule or with adjustme…
Phase 4 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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New eye injection shows promise for diabetic vision loss
Disease control CompletedThis phase 2 trial tested a new way to deliver dexamethasone directly to the back of the eye using tiny microspheres (OXU-001) compared to the standard Ozurdex implant. The study enrolled only 3 adults with diabetic macular edema to check safety and how well the treatment is tole…
Phase 2 • Sponsor: Oxular Limited • Aim: Disease control
Last updated Jun 26, 2026 13:03 UTC
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Could a smartphone camera spot blinding eye diseases?
Diagnosis CompletedThis study tests whether a smartphone-based camera can accurately screen for eye diseases such as diabetic retinopathy, glaucoma, and age-related macular degeneration. About 550 patients will have photos taken with both the smartphone camera and standard equipment. Ophthalmologis…
Sponsor: University of Michigan • Aim: Diagnosis
Last updated Aug 22, 2026 00:00 UTC
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New eye scanner could sharpen diagnosis of glaucoma and retina diseases
Diagnosis CompletedThis study is testing a new eye imaging device called the VG200D, which uses advanced technology to take detailed pictures of the eye. Researchers want to see if it works as well as a standard device for measuring parts of the eye in people with glaucoma, retina problems, corneal…
Sponsor: Intalight, Inc • Aim: Diagnosis
Last updated Jul 31, 2026 00:00 UTC
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New eye test could spot retinal disease faster
Diagnosis CompletedThis study tested a device called RETeval that measures how the retina responds to light. Researchers collected data from 664 people, both with and without retinal disease, to create a reference for normal eye function. The goal is to improve diagnosis of retinal conditions.
Sponsor: LKC Technologies, Inc. • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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New eye drop could ease pain of Sight-Saving injections
Symptom relief CompletedThis study tested a new antiseptic called IRX-101 against the standard povidone-iodine in 155 people receiving eye injections for retinal disease. The goal was to see if IRX-101 reduces pain and corneal damage after the injection. Researchers measured safety and corneal staining …
Phase 2 • Sponsor: iRenix Medical, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Soothing sounds: slow music eases anxiety during eye procedures
Symptom relief CompletedThis study tested whether playing slow tempo music before and during an eye injection (intravitreal injection) can reduce anxiety and pain. 144 adults took part, with half listening to music and the other half receiving standard care. Researchers measured anxiety using saliva tes…
Sponsor: Ng Yu Siang • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Can a steroid drop take the sting out of eye injections?
Symptom relief CompletedThis study tested whether a steroid eye drop (loteprednol) can reduce pain after intravitreal injections for age-related macular degeneration. 64 participants received either the steroid drop or artificial tears right after their injection. Pain was tracked by phone over a week. …
Sponsor: Virginia Polytechnic Institute and State University • Aim: Symptom relief
Last updated Jun 26, 2026 19:06 UTC
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Study checks if past drug still protects kidneys years later
Knowledge-focused CompletedThis study looks at American Indians with type 2 diabetes who had early kidney disease and took a drug called losartan years ago. Researchers want to see if the benefits of that treatment still help protect their kidneys today. About 141 people who were in the earlier study or th…
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Sep 10, 2026 00:00 UTC
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Built-In eye scanner could give surgeons a live 3D view during operations
Knowledge-focused CompletedThis study tests a microscope that has an OCT scanner built directly into it, allowing surgeons to take detailed cross-sectional images of the eye during surgery. The goal is to see if this setup is practical and whether the extra visual information helps guide surgical decisions…
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Aug 05, 2026 00:00 UTC
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New eye scanner aims to sharpen view of retinal disease
Knowledge-focused CompletedThis trial tests a new device called P200TxE that takes detailed images of the back of the eye. Researchers want to see how well it captures images in people with retinal diseases like glaucoma or macular degeneration. The study involves adults aged 22 and older who have been dia…
Sponsor: Optos, PLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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AI boosts eye Doctors' accuracy in reading retinal scans?
Knowledge-focused CompletedThis study tested whether artificial intelligence (AI) can help doctors detect retinal diseases from ultra-widefield eye images. 462 images were read by four eye doctors with different experience levels, both with and without AI assistance. The goal was to see if AI improves accu…
Sponsor: Xiamen Ophthalmology Center Affiliated to Xiamen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Does the type of eye tamponade affect retinal shift after detachment repair?
Knowledge-focused CompletedThis study looked at 78 people in Pakistan who had surgery for a detached retina. Doctors compared two types of fillers used inside the eye after surgery—gas or silicone oil—to see if one caused more shifting of the retina afterward. The goal was to learn how the choice of filler…
Sponsor: Wardah • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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New device may speed up eye exams by skipping dilation drops
Knowledge-focused CompletedThis study tested a device called RETeval that measures the retina's electrical activity in response to light flashes. Researchers wanted to see if changing the flash color or skipping pupil dilation still gives useful results. 18 healthy adults participated. The goal is to make …
Sponsor: LKC Technologies, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Eye scans could predict vision loss in diabetes patients
Knowledge-focused CompletedThis study looked at 202 adults with type 2 diabetes and early-stage diabetic eye disease (non-proliferative diabetic retinopathy). Researchers used non-invasive eye scans to find markers that could predict if the disease would get worse or lead to sight-threatening problems. The…
Sponsor: Association for Innovation and Biomedical Research on Light and Image • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Iron overload linked to blindness risk in preemies?
Knowledge-focused CompletedThis study looked at 175 premature babies to see if high iron levels in their blood during the first month of life are linked to a serious eye condition called retinopathy of prematurity (ROP). Researchers measured iron-related markers and tracked which babies developed ROP. The …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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New eye scanner works even when You're flat on your back
Knowledge-focused CompletedThis study tested a special eye imaging device that can take pictures of the retina while a person lies down. Researchers compared images from the new device to those from a standard upright device in 88 adults with healthy eyes or retinal disease. The goal was to see if the new …
Sponsor: Heidelberg Engineering GmbH • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:06 UTC