New eye drop could make retina injections less painful
NCT ID NCT05747430
First seen Apr 14, 2026 · Last updated Jun 23, 2026 · Updated 11 times
Summary
This study tested a new antiseptic called IRX-101 against the standard povidone-iodine in 155 people receiving eye injections for retinal disease. The goal was to see if IRX-101 causes less pain and less damage to the cornea. Researchers measured safety and corneal staining to compare the two treatments.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Charleston Neuroscience Institute
Ladson, South Carolina, 29456, United States
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Coastal Eye Surgeons, LLC
Greenwich, Connecticut, 06830, United States
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Edward Wood, MD
Round Rock, Texas, 78681, United States
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Erie Retina Research, LLC
Erie, Pennsylvania, 16507, United States
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Mississippi Retina Associates
Madison, Mississippi, 39110, United States
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Retina Associates of Utah
Salt Lake City, Utah, 84107, United States
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Retina Consultants of Texas
Katy, Texas, 77494, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
IRX-101 (a novel eye antiseptic)
What this could lead to
If it works, IRX-101 could make eye injections less painful and reduce damage to the cornea, improving comfort for people with retinal disease.
What could go wrong
This is a small, early-phase trial (155 people) testing a new drug. It may not prove better than the standard antiseptic, and safety is still being checked.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.