New eye drop could ease pain of Sight-Saving injections

NCT ID NCT05747430

Completed Symptom relief Sponsor: iRenix Medical, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new antiseptic called IRX-101 against the standard povidone-iodine in 155 people receiving eye injections for retinal disease. The goal was to see if IRX-101 reduces pain and corneal damage after the injection. Researchers measured safety and corneal staining to compare the two treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: IRX-101 (a novel antiseptic solution)
What this could lead to: If it works, this could make eye injections for retinal disease less painful and reduce damage to the cornea, improving patient comfort.
What could go wrong: This is a small, early-phase trial (Phase 2) with only 155 participants. The results may not apply to everyone, and the new antiseptic might not be better than the standard one.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

retinal disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RETINAL DISEASE

Contacts and locations

Locations

Charleston Neuroscience Institute

Ladson, South Carolina, 29456, United States
Coastal Eye Surgeons, LLC

Greenwich, Connecticut, 06830, United States
Edward Wood, MD

Round Rock, Texas, 78681, United States
Erie Retina Research, LLC

Erie, Pennsylvania, 16507, United States
Mississippi Retina Associates

Madison, Mississippi, 39110, United States
Retina Associates of Utah

Salt Lake City, Utah, 84107, United States
Retina Consultants of Texas

Katy, Texas, 77494, United States

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