RETINAL DISEASE

This study is testing an experimental drug called ultevursen, given as an injection into the eye, for people with a specific genetic type of retinitis pigmentosa (RP). The goal is to see if it can slow down the loss of vision over two years. About 81 participants will be randomly…

This study is testing whether regular eye injections of an experimental drug called sepofarsen can improve vision in people with a specific genetic form of Leber congenital amaurosis (LCA), which causes severe vision loss from childhood. In this carefully designed trial, each par…

This study is testing the safety and effectiveness of repeat injections of an experimental drug, VP-001, into the eye. It is for adults with a rare, inherited form of vision loss called PRPF31 mutation-associated retinal dystrophy. The goal is to see if the injections can help co…

This study is testing a new 3D imaging system that gives eye surgeons a live, detailed view inside the eye during surgery. The goal is to see if this technology helps surgeons perform delicate procedures more precisely and safely. The study is enrolling patients undergoing variou…

This study is testing a new, easier-to-use version of a handheld eye scanner. The goal is to see if its automatic alignment feature can take clear pictures of the back of the eye (retina) in both adults and children. Researchers will enroll 50 volunteers and patients to see how w…

This study aims to compare two types of handheld eye scanners to see which works better for imaging children's retinas. Researchers will test both a contact scanner and a non-contact scanner on 20 pediatric patients and 10 healthy adults. The goal is to determine which system pro…

This study aims to understand how diabetic eye disease (retinopathy) gets worse over time. Researchers will use advanced, non-invasive eye scans to closely monitor 100 patients with moderate to severe diabetic retinopathy for two years. The goal is to identify early warning signs…

This study aims to understand why some people develop serious eye damage from Plaquenil (hydroxychloroquine), a drug used for lupus and arthritis, while most do not. Researchers will compare the genes of people who have experienced this eye damage with those who have taken the dr…

This study aims to understand a rare genetic disease called pseudoxanthoma elasticum (PXE) by looking at blood flow in the back of the eye. Researchers will compare detailed eye scans from 60 healthy volunteers to scans from 60 patients with PXE. The goal is to see if changes in …

This study aims to collect detailed scan images of the eye from 180 people. It includes participants with various eye conditions like macular degeneration, glaucoma, and corneal diseases, as well as people with healthy eyes. The goal is to build a large database of images to help…

This study is testing a new digital platform called the Genetics Navigator. It's designed to help guide patients and parents through the complex process of genetic testing for conditions like cancer, heart disease, and epilepsy. Researchers want to see if using this online tool r…

This study aims to understand and eventually find treatments for serious eye diseases that can lead to blindness, like macular degeneration. Researchers will collect simple samples like hair, skin, or blood from people with these conditions and from healthy volunteers. In the lab…

This study aims to compare two newer, wide-angle eye cameras to the current standard camera to see if they provide the same quality of information for monitoring inherited retinal diseases. Researchers will take pictures of the back of the eye using all three cameras in about 50 …

This study is creating a research database by collecting health information and physical samples from people with and without eye diseases. Researchers will follow 650 participants over time, including those with conditions like macular degeneration and diabetic retinopathy, as w…