New eye injection shows promise for rare Blindness-Causing gene mutation
NCT ID NCT06455826
First seen Apr 16, 2026 · Last updated Jun 16, 2026 · Updated 14 times
Summary
This early-stage study tested the safety of a new drug called VP-001, given as an injection into the eye, for people with a rare genetic eye disease (PRPF31 mutation) that causes vision loss. Six participants aged 12 and older received multiple doses. The main goal was to check for side effects, not to measure vision improvement.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Baylor College of Medicine- Alkek Eye Center
Houston, Texas, 77030, United States
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Oregon Health and Science University - Casey Eye Institute
Portland, Oregon, 97239, United States
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Retina Foundation of the Southwest
Dallas, Texas, 75321, United States
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University of Florida Health
Jacksonville, Florida, 32209, United States
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University of Michigan Kellogg Eye Center
Ann Arbor, Michigan, 48105, United States
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.