Prosthesis-related infectious disease

This study looked at whether a custom-made hip spacer can help people with infected hip replacements. 25 patients had their infected hip implant removed and replaced with a temporary custom spacer, followed by antibiotics. After the infection cleared, they received a new permanen…

Dental implants can fail when bacteria leak into the hollow space inside the implant, causing infection and bone loss. This trial tests whether placing a dab of antiseptic gel — either chlorhexidine or hydrogen peroxide — inside the implant during surgery can reduce bacterial gro…

This study tested a special bandage (dressing) that contains a germ-killing ingredient called chlorhexidine for IV tubes placed in the arm. The goal was to see if it reduces infections and other complications compared to the standard bandage. About 300 patients in Australia and F…

This study tested whether a silver-coated dressing (Silverlon) could reduce infections where the LVAD driveline exits the body. Twenty-five adults with a new LVAD were randomly assigned to receive either the silver dressing or a standard one. Researchers tracked infection rates, …

This study compared 6 weeks versus 12 weeks of antibiotics for people with infected hip or knee prostheses who had surgery. Researchers wanted to see if the shorter course was just as effective at curing the infection without increasing relapse. The trial enrolled 410 adults acro…

This study tests a new radioactive tracer called [F-18]MHF to see if it can detect infections around knee implants using PET scans. Researchers will compare the tracer's uptake in infected versus non-infected implants in 18 adults. The goal is to improve diagnosis and reduce unne…

This study compared staph bacteria from 57 patients with implant infections to 31 from healthy nasal carriers. Researchers looked at the bacteria's genes and ability to form biofilms (slimy coatings). The goal was to find what makes some staph strains more dangerous around implan…

This study looked back at medical records of 397 patients who had surgery for a broken shinbone (tibia) using either an antibiotic-coated or a standard uncoated titanium nail. The goal was to see if the coated nail reduced infections and improved bone healing. Researchers also ch…

This study examined nearly 100,000 people who had knee replacement for arthritis to see if those who previously had weight-loss surgery faced different risks of complications or needing another surgery. Researchers focused on how body weight at the time of knee replacement and th…

This completed study looked at 500 patients who had abdominal wall prosthesis infections after hernia surgery. Researchers aimed to identify risk factors, common germs, and what helps patients recover. The goal is to improve how these infections are managed.